Rui Xiao

Rui Xiao, Ph.D.

Assistant Professor

Department: MD-BIOLOGY OF AGING
Business Phone: (352) 273-9389
Business Email: rxiao@ufl.edu

Publications

2021
A novel role of the mitochondrial iron-sulfur cluster assembly protein ISCU-1/ISCU in longevity and stress response.
GeroScience. [DOI] 10.1007/s11357-021-00327-z. [PMID] 33527323.
2021
Fungal Epithiodiketopiperazines Carrying α,β-Polysulfide Bridges from Penicillium steckii YE, and Their Chemical Interconversion.
Chembiochem : a European journal of chemical biology. 22(2):416-422 [DOI] 10.1002/cbic.202000403. [PMID] 32816319.
2021
The role of neurosensory systems in the modulation of aging
Handbook of the Biology of Aging. 285-295 [DOI] 10.1016/b978-0-12-815962-0.00013-5.
2020
Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older Adults.
Cells. 9(12) [DOI] 10.3390/cells9122579. [PMID] 33276460.
2020
BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome.
Brain structure & function. 225(6):1743-1760 [DOI] 10.1007/s00429-020-02090-x. [PMID] 32468214.
2020
Deficiency of Meis1, a transcriptional regulator, in mice and worms: Neurochemical and behavioral characterizations with implications in the restless legs syndrome.
Journal of neurochemistry. 155(5):522-537 [DOI] 10.1111/jnc.15177. [PMID] 32910473.
2020
Distinct temporal actions of different types of unfolded protein responses during aging.
Journal of cellular physiology. [DOI] 10.1002/jcp.30215. [PMID] 33345326.
2020
Innovations in Geroscience to enhance mobility in older adults
Experimental Gerontology. [DOI] 10.1016/j.exger.2020.111123. [PMID] 33191210.
2020
Probing the relationship between BTBD9 and MEIS1 in C. elegans and mouse
Experimental Results. 1(e8) [DOI] https://doi.org/10.1017/exp.2020.12.
2020
Temperature Sensation: From Molecular Thermosensors to Neural Circuits and Coding Principles.
Annual review of physiology. [DOI] 10.1146/annurev-physiol-031220-095215. [PMID] 33085927.
2019
Distinct functions of TMC channels: a comparative overview.
Cellular and molecular life sciences : CMLS. 76(21):4221-4232 [DOI] 10.1007/s00018-019-03214-1. [PMID] 31584127.
2018
Brain-gut communications via distinct neuroendocrine signals bidirectionally regulate longevity in C. elegans.
Genes & development. 32(3-4):258-270 [DOI] 10.1101/gad.309625.117. [PMID] 29491136.
2018
Decoding the intensity of sensory input by two glutamate receptors in one C. elegans interneuron.
Nature communications. 9(1) [DOI] 10.1038/s41467-018-06819-5. [PMID] 30333484.
2018
TMC Proteins Modulate Egg Laying and Membrane Excitability through a Background Leak Conductance in C. elegans.
Neuron. 97(3):571-585.e5 [DOI] 10.1016/j.neuron.2017.12.041. [PMID] 29395910.
2017
Membrane ion Channels and Receptors in Animal lifespan Modulation.
Journal of cellular physiology. 232(11):2946-2956 [DOI] 10.1002/jcp.25824. [PMID] 28121014.
2015
Environmental Temperature Differentially Modulates C. elegans Longevity through a Thermosensitive TRP Channel.
Cell reports. 11(9):1414-24 [DOI] 10.1016/j.celrep.2015.04.066. [PMID] 26027928.
2015
RNAi Interrogation of Dietary Modulation of Development, Metabolism, Behavior, and Aging in C. elegans.
Cell reports. 11(7):1123-33 [DOI] 10.1016/j.celrep.2015.04.024. [PMID] 25959815.
2015
Thermosensation and longevity.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 201(9):857-67 [DOI] 10.1007/s00359-015-1021-8. [PMID] 26101089.
2013
A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel.
Cell. 152(4):806-17 [DOI] 10.1016/j.cell.2013.01.020. [PMID] 23415228.
2011
C. elegans TRP channels.
Advances in experimental medicine and biology. 704:323-39 [DOI] 10.1007/978-94-007-0265-3_18. [PMID] 21290304.
2011
Studying TRP Channels in
TRP Channels. [PMID] 22593955.
View on: PubMed
2010
Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs.
Pflugers Archiv : European journal of physiology. 459(4):579-92 [DOI] 10.1007/s00424-009-0749-9. [PMID] 19888597.
2010
Mechanosensitive channels: in touch with Piezo.
Current biology : CB. 20(21):R936-8 [DOI] 10.1016/j.cub.2010.09.053. [PMID] 21056836.
2009
Dopamine modulates an mGluR5-mediated depolarization underlying prefrontal persistent activity.
Nature neuroscience. 12(2):190-9 [DOI] 10.1038/nn.2245. [PMID] 19169252.
2009
Function and regulation of TRP family channels in C. elegans.
Pflugers Archiv : European journal of physiology. 458(5):851-60 [DOI] 10.1007/s00424-009-0678-7. [PMID] 19421772.
2009
NAADP mobilizes calcium from acidic organelles through two-pore channels.
Nature. 459(7246):596-600 [DOI] 10.1038/nature08030. [PMID] 19387438.
2008
Calcium plays a central role in the sensitization of TRPV3 channel to repetitive stimulations.
The Journal of biological chemistry. 283(10):6162-74 [DOI] 10.1074/jbc.M706535200. [PMID] 18178557.
2008
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate.
The Journal of biological chemistry. 283(15):10026-36 [DOI] 10.1074/jbc.M707306200. [PMID] 18230622.
2008
The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active.
Cell calcium. 43(4):334-43 [PMID] 17706768.
View on: PubMed
2007
The axon-dendrite targeting of Kv3 (Shaw) channels is determined by a targeting motif that associates with the T1 domain and ankyrin G.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(51):14158-70 [PMID] 18094255.
View on: PubMed
2006
Potentiation of TRPV3 channel function by unsaturated fatty acids.
Journal of cellular physiology. 208(1):201-12 [PMID] 16557504.
View on: PubMed
2005
Calmodulin and calcium interplay in the modulation of TRPC5 channel activity. Identification of a novel C-terminal domain for calcium/calmodulin-mediated facilitation.
The Journal of biological chemistry. 280(35):30788-96 [PMID] 15987684.
View on: PubMed
2005
Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes.
Pflugers Archiv : European journal of physiology. 450(5):345-54 [PMID] 15895247.
View on: PubMed
2004
Mutual dependence of VIP/PACAP and CCK receptor signaling for a physiological role in duck exocrine pancreatic secretion.
American journal of physiology. Regulatory, integrative and comparative physiology. 286(1):R189-98 [PMID] 12947031.
View on: PubMed
2003
Selective activation by photodynamic action of cholecystokinin receptor in the freshly isolated rat pancreatic acini.
British journal of pharmacology. 139(4):872-80 [PMID] 12813011.
View on: PubMed

Education

Post-Doc, Genetics
2009-2015 · Life Sciences Institute, University of Michigan
Ph.D. in Biophysics
2008 · Ohio State University
Master of Science in Cell Biology
2003 · Beijing Normal University
Bachelor of Science in Biology
2000 · Beijing Normal University, Beijing China

Teaching Profile

Courses Taught
2017-2021
GMS6487 Anti-aging Interventions
2018-2021
GMS6099 Research Methods in Gerontology
2017-2019,2021
GMS6070 Sensory and Motor Systems
2018
GMS7980 Research for Doctoral Dissertation
2016
GMS6893 Clinical and Translational Science Seminar Series

Contact Details

Phones:
Business:
(352) 273-9389
Emails:
Business:
rxiao@ufl.edu