Kimberly Sibille

Kimberly Sibille, Ph.D., M.A.

Associate Professor; Director Of The Pain TRAIL

Department: MD-AGING-CLINICAL RESEARCH
Business Phone: (352) 294-5846
Business Email: ksibille@ufl.edu

About Kimberly Sibille

Employment and Training

Dr. Sibille is an Associate Professor in the Department of Aging & Geriatric Research and the Department of Anesthesiology, Division of Pain Medicine in the College of Medicine. She is an Affiliate Faculty member in the Pain Research and Intervention Center of Excellence (PRICE) and the School of Advanced Dental Sciences (SADS), College of Dentistry.

Dr. Sibille earned a doctoral degree in Psychology/Clinical Psychology with concentrations in Neuropsychology and Health Psychology from Fielding Graduate University and completed post-doctoral training in Clinical and Translational Pain Research through the UF Comprehensive Center for Pain Research. Her research efforts benefit from her background in exercise science; graduate training in Counselor Education; over fifteen years of clinical practice in diverse healthcare settings; and experiences teaching and training healthcare professionals, graduate students, and medical and dental residents.

Honors and Awards

Dr. Sibille received the 2017-2018 College of Medicine’s University of Florida Term Professorship and the 2017 University of Florida Research Excellence Award for Assistant Professors. She is currently funded by the National Institute on Aging (NIA) and the National Institute for Mental Health (NIMH). Previous research funding has been awarded from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the 2014 American Pain Society Sharon S. Keller Chronic Pain Research Grant; the 2014 UF Clinical and Translational Science Institute (CTSI) Patient-Oriented Pilot Award; the 2012 International Association for the Study of Pain Grant funded by Scan/Design by the Inger & Jens Bruun Foundation; the 2012 UF CTSI KL2 Scholar and Institute on Aging Pepper Junior Scholar Award; and the 2010 American Pain Society Future Leaders in Pain Research Award.

Research Profile

Inspired by experiences working in healthcare, research from my lab focuses on bridging the biomedical and psychosocial chasm in chronic pain. Chronic pain is a major public health issue with significant functional and financial consequences affecting individuals, the community, and the healthcare system. Even more concerning, the consequences of chronic pain extend beyond disability and decreased quality of life to include an increased incidence of morbidity and mortality. Research investigation and clinical management of chronic pain is difficult due to significant individual variability and the lack of biological indices with which to evaluate risk and protective factors, progression, and treatment response.

Our scientific pursuits are specific to investigating the interactive influences of biological, psychosocial, cognitive, and behavioral factors associated with osteoarthritis and other musculoskeletal chronic pain conditions with an emphasis on stress, aging, health disparities, and resilience. The intentions underlying our investigations are to 1) elucidate biological measures reflecting the stress-related biological burden resulting from chronic pain conditions; 2) delineate resilience and vulnerability factors for prevention and treatment; and 3) identify biobehavioral strategies to optimize chronic pain treatment interventions. The overarching goals of our efforts are to contribute to the research and medical community by improving the understanding of the biological interface of chronic pain and associated stressors, to formulate a clinical composite for assessing and evaluating treatment interventions, and to identify strategies and targets to prevent, reduce or ameliorate chronic pain.

https://aging.ufl.edu/research/the-pain-TRAIL/

Publications

2021
Assessing the feasibility of using the short physical performance battery to measure function in the immediate postoperative period after total knee replacement.
European journal of translational myology. [DOI] 10.4081/ejtm.2021.9673. [PMID] 33840178.
2021
Relationships Between Chronic Pain Stage, Cognition, Temporal Lobe Cortex, and Sociodemographic Variables.
Journal of Alzheimer's disease : JAD. 80(4):1539-1551 [DOI] 10.3233/JAD-201345. [PMID] 33720889.
2021
Resilience, pain, and the brain: Relationships differ by sociodemographics.
Journal of neuroscience research. 99(5):1207-1235 [DOI] 10.1002/jnr.24790. [PMID] 33606287.
2020
Associations of pain catastrophizing with pain-related brain structure in individuals with or at risk for knee osteoarthritis: Sociodemographic considerations.
Brain imaging and behavior. [DOI] 10.1007/s11682-020-00372-w. [PMID] 33095381.
2020
Determinants of Adherence in Time-Restricted Feeding in Older Adults: Lessons from a Pilot Study.
Nutrients. 12(3) [DOI] 10.3390/nu12030874. [PMID] 32213965.
2020
Everyday Discrimination in Adults with Knee Pain: The Role of Perceived Stress and Pain Catastrophizing.
Journal of pain research. 13:883-895 [DOI] 10.2147/JPR.S235632. [PMID] 32431537.
2020
Innovations in Geroscience to enhance mobility in older adults.
Experimental gerontology. 142 [DOI] 10.1016/j.exger.2020.111123. [PMID] 33191210.
2020
Neuropathic-Like Pain Symptoms in a Community-Dwelling Sample with or at Risk for Knee Osteoarthritis.
Pain medicine (Malden, Mass.). 21(1):125-137 [DOI] 10.1093/pm/pnz112. [PMID] 31150093.
2020
Pain relief for osteoarthritis through combined treatment (PROACT): Protocol for a randomized controlled trial of mindfulness meditation combined with transcranial direct current stimulation in non-Hispanic black and white adults with knee osteoarthritis.
Contemporary clinical trials. 98 [DOI] 10.1016/j.cct.2020.106159. [PMID] 32992020.
2020
Patterns and correlates of self-management strategies for osteoarthritis related pain among older non-Hispanic Black and non-Hispanic White adults.
Arthritis care & research. [DOI] 10.1002/acr.24396. [PMID] 32741127.
2020
Psychological Predictors of Perceived Age and Chronic Pain Impact in Individuals With and Without Knee Osteoarthritis.
The Clinical journal of pain. 36(8):569-577 [DOI] 10.1097/AJP.0000000000000842. [PMID] 32398442.
2020
Re-test reliability and internal consistency of EEG alpha-band oscillations in older adults with chronic knee pain.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 131(11):2630-2640 [DOI] 10.1016/j.clinph.2020.07.022. [PMID] 32947197.
2020
Relationships Between Pain, Life Stress, Sociodemographics, and Cortisol: Contributions of Pain Intensity and Financial Satisfaction.
Chronic stress (Thousand Oaks, Calif.). 4 [DOI] 10.1177/2470547020975758. [PMID] 33403312.
2019
At the Intersection of Ethnicity/Race and Poverty: Knee Pain and Physical Function.
Journal of racial and ethnic health disparities. 6(6):1131-1143 [DOI] 10.1007/s40615-019-00615-7. [PMID] 31292922.
2019
Blood-Flow Restriction Resistance Exercise for Older Adults with Knee Osteoarthritis: A Pilot Randomized Clinical Trial.
Journal of clinical medicine. 8(2) [DOI] 10.3390/jcm8020265. [PMID] 30795545.
2019
Movement-evoked pain, physical function, and perceived stress: An observational study of ethnic/racial differences in aging non-Hispanic Blacks and non-Hispanic Whites with knee osteoarthritis.
Experimental gerontology. 124 [DOI] 10.1016/j.exger.2019.05.011. [PMID] 31154005.
2019
Race/Ethnicity Moderates the Association Between Psychosocial Resilience and Movement-Evoked Pain in Knee Osteoarthritis.
ACR open rheumatology. 1(1):16-25 [DOI] 10.1002/acr2.1002. [PMID] 31777776.
2019
Resilience factors may buffer cellular aging in individuals with and without chronic knee pain.
Molecular pain. 15 [DOI] 10.1177/1744806919842962. [PMID] 30900507.
2018
Omega-6: Omega-3 PUFA Ratio, Pain, Functioning, and Distress in Adults With Knee Pain.
The Clinical journal of pain. 34(2):182-189 [DOI] 10.1097/AJP.0000000000000517. [PMID] 28542024.
2018
Optimism and Psychological Resilience are Beneficially associated with Measures of Clinical and Experimental Pain in Adults with or at Risk for Knee Osteoarthritis.
The Clinical journal of pain. 34(12):1164-1172 [DOI] 10.1097/AJP.0000000000000642. [PMID] 30036216.
2017
Accelerated aging in adults with knee osteoarthritis pain: consideration for frequency, intensity, time, and total pain sites.
Pain reports. 2(3) [DOI] 10.1097/PR9.0000000000000591. [PMID] 29392207.
2017
Allostatic load and pain severity in older adults: Results from the English Longitudinal Study of Ageing.
Experimental gerontology. 88:51-58 [DOI] 10.1016/j.exger.2016.12.013. [PMID] 27988258.
2017
An update on myofibromas and myofibromatosis affecting the oral regions with report of 24 new cases.
Oral surgery, oral medicine, oral pathology and oral radiology. 124(1):62-75 [DOI] 10.1016/j.oooo.2017.03.051. [PMID] 28522188.
2017
Physical performance and movement-evoked pain profiles in community-dwelling individuals at risk for knee osteoarthritis.
Experimental gerontology. 98:186-191 [DOI] 10.1016/j.exger.2017.08.026. [PMID] 28842222.
2017
Single Nucleotide Polymorphism in the COL11A2 Gene Associated with Heat Pain Sensitivity in Knee Osteoarthritis.
Molecular pain. 13 [DOI] 10.1177/1744806917724259. [PMID] 28741447.
2016
Affect and Low Back Pain: More to Consider Than the Influence of Negative Affect Alone.
The Clinical journal of pain. 32(10):907-14 [DOI] 10.1097/AJP.0000000000000350. [PMID] 26889620.
2016
Enhanced Pain Sensitivity Among Individuals With Symptomatic Knee Osteoarthritis: Potential Sex Differences in Central Sensitization.
Arthritis care & research. 68(4):472-80 [DOI] 10.1002/acr.22712. [PMID] 26434740.
2016
Experimental pain phenotyping in community-dwelling individuals with knee osteoarthritis.
Pain. 157(9):2104-2114 [DOI] 10.1097/j.pain.0000000000000625. [PMID] 27340911.
2016
Increasing Neuroplasticity to Bolster Chronic Pain Treatment: A Role for Intermittent Fasting and Glucose Administration?
The journal of pain. 17(3):275-81 [DOI] 10.1016/j.jpain.2015.11.002. [PMID] 26848123.
2016
Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite.
Pain research & management. 2016 [DOI] 10.1155/2016/7657329. [PMID] 27445627.
2015
A Cross-sectional Examination of Vitamin D, Obesity, and Measures of Pain and Function in Middle-aged and Older Adults With Knee Osteoarthritis.
The Clinical journal of pain. 31(12):1060-7 [DOI] 10.1097/AJP.0000000000000210. [PMID] 25569220.
2015
Disrupted sleep is associated with altered pain processing by sex and ethnicity in knee osteoarthritis.
The journal of pain. 16(5):478-90 [DOI] 10.1016/j.jpain.2015.02.004. [PMID] 25725172.
2015
Kaatsu training to enhance physical function of older adults with knee osteoarthritis: Design of a randomized controlled trial.
Contemporary clinical trials. 43:217-22 [DOI] 10.1016/j.cct.2015.06.016. [PMID] 26111922.
2015
Physical Function and Associated Pain in Knee Osteoarthritis (Oa) Predicts Sensory Processing and Future Clinical Pain Experiences
Journal of Pain. 16(4, 1)
2015
Successful aging: Advancing the science of physical independence in older adults.
Ageing research reviews. 24(Pt B):304-27 [DOI] 10.1016/j.arr.2015.09.005. [PMID] 26462882.
2014
Age and race effects on pain sensitivity and modulation among middle-aged and older adults.
The journal of pain. 15(3):272-82 [DOI] 10.1016/j.jpain.2013.10.015. [PMID] 24239561.
2014
Pain hypervigilance is associated with greater clinical pain severity and enhanced experimental pain sensitivity among adults with symptomatic knee osteoarthritis.
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine. 48(1):50-60 [DOI] 10.1007/s12160-013-9563-x. [PMID] 24352850.
2014
Psychological Resilience as a Predictor of Pain and Stress in Symptomatic Knee Osteoarthritis
Psychosomatic Medicine. 76(3):A2-A3
2014
Racial and ethnic differences in older adults with knee osteoarthritis.
Arthritis & rheumatology (Hoboken, N.J.). 66(7):1800-10 [DOI] 10.1002/art.38620. [PMID] 24729357.
2014
Temporal summation of pain as a prospective predictor of clinical pain severity in adults aged 45 years and older with knee osteoarthritis: ethnic differences.
Psychosomatic medicine. 76(4):302-10 [DOI] 10.1097/PSY.0000000000000058. [PMID] 24804882.
2013
Experimental Pain Sensitivity Differs as a Function of Clinical Pain Severity in Symptomatic Knee Osteoarthritis (Vol 21, Pg 1243, 2013)
Osteoarthritis and Cartilage. 21(11) [DOI] 10.1016/j.joca.2013.09.001.
2013
Experimental pain sensitivity differs as a function of clinical pain severity in symptomatic knee osteoarthritis.
Osteoarthritis and cartilage. 21(9):1243-52 [DOI] 10.1016/j.joca.2013.05.015. [PMID] 23973137.
2013
Perceived racial discrimination, but not mistrust of medical researchers, predicts the heat pain tolerance of African Americans with symptomatic knee osteoarthritis.
Health psychology : official journal of the Division of Health Psychology, American Psychological Association. 32(11):1117-26 [DOI] 10.1037/a0031592. [PMID] 24219416.
2013
Psychological profiles and pain characteristics of older adults with knee osteoarthritis.
Arthritis care & research. 65(11):1786-94 [PMID] 23861288.
View on: PubMed
2013
Psychosocial Profiles and Pain Characteristics of Older Adults With Knee Osteoarthritis
Journal of Pain. 14
2013
Testing the relation between dispositional optimism and conditioned pain modulation: does ethnicity matter?
Journal of behavioral medicine. 36(2):165-74 [DOI] 10.1007/s10865-012-9411-7. [PMID] 22367226.
2013
The association of greater dispositional optimism with less endogenous pain facilitation is indirectly transmitted through lower levels of pain catastrophizing.
The journal of pain. 14(2):126-35 [DOI] 10.1016/j.jpain.2012.10.007. [PMID] 23218934.
2013
The Role of Race and Sex On Experimental Pain Sensitivity in Individuals With Symptomatic Knee Osteoarthritis
Journal of Pain. 14
2012
Affect balance style, experimental pain sensitivity, and pain-related responses.
The Clinical journal of pain. 28(5):410-7 [DOI] 10.1097/AJP.0b013e3182324799. [PMID] 22367502.
2012
Authors build an important foundation for further research.
The journal of pain. 13(12):1269-70 [DOI] 10.1016/j.jpain.2012.09.010. [PMID] 23182232.
2012
Chronic pain, perceived stress, and cellular aging: an exploratory study.
Molecular pain. 8 [DOI] 10.1186/1744-8069-8-12. [PMID] 22325162.
2012
Telomeres and epigenetics: potential relevance to chronic pain.
Pain. 153(9):1789-1793 [DOI] 10.1016/j.pain.2012.06.003. [PMID] 22770844.
2012
Vitamin D, race, and experimental pain sensitivity in older adults with knee osteoarthritis.
Arthritis and rheumatism. 64(12):3926-35 [DOI] 10.1002/art.37687. [PMID] 23135697.
2011
Drug response profiles to experimental pain are opioid and pain modality specific.
The journal of pain. 12(3):340-51 [DOI] 10.1016/j.jpain.2010.07.011. [PMID] 21146469.
2011
Individual differences in morphine and butorphanol analgesia: a laboratory pain study.
Pain medicine (Malden, Mass.). 12(7):1076-85 [DOI] 10.1111/j.1526-4637.2011.01157.x. [PMID] 21668741.
2010
Decisional Capacity among Minors with HIV: A Model for Balancing Autonomy Rights with the Need for Protection.
Ethics & behavior. 20(2):83-94 [PMID] 26568667.
View on: PubMed
2010
Factors Contributing To the Maintenance of Chronic Pain: Relevance for Treatment
Annals of Behavioral Medicine. 39
2010
Medical decisional capacity among children with HIV.
AIDS care. 22(11):1359-66 [DOI] 10.1080/09540121003758499. [PMID] 20686987.
2010
Preparing Physicians for the 21 Century: Targeting Communication Skills and the Promotion of Health Behavior Change.
Annals of behavioral science and medical education : journal of the Association for the Behavioral Sciences and Medical Education. 16(1):7-13 [PMID] 22187518.
View on: PubMed
2007
Family medicine physicians’ advice about use of nonconventional modalities for menopausal symptom management.
Journal of women's health (2002). 16(4):517-25 [PMID] 17521255.
View on: PubMed
2006
Treatment of menopausal symptoms in family medicine settings following the Women’s Health Initiative findings.
Journal of the American Board of Family Medicine : JABFM. 19(2):122-31 [PMID] 16513900.
View on: PubMed

Grants

May 2020 ACTIVE
Biobehavioral basis of knee osteoarthritis pain
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Jun 2019 ACTIVE
Ethnic Differences in Responses to Painful Stimuli
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Sep 2018 ACTIVE
Adaptability and Resilience in Aging Adults (ARIAA)
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
May 2017 ACTIVE
Emotional Engagement Driven by Complex Visual Stimuli: Neural Dynamics Revealed by Multimodal Imaging
Role: Co-Investigator
Funding: NATL INST OF HLTH NIMH
Jan 2017 ACTIVE
Sibille Misc Donors
Role: Principal Investigator
Funding: MISCELLANEOUS DONORS
Sep 2016 ACTIVE
Health Disparities in Osteoarthritis: Biological Aging, Stress, and Pain – Modulation by Resilience Factors
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Sep 2014 – May 2019
Ethnic Differences in Responses to Painful Stimuli
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Jun 2014 – Sep 2017
Optimizing Chronic Pain Treatment with Enhanced Neuroplastic Responsiveness
Role: Principal Investigator
Funding: AMER PAIN SOCIETY
Apr 2013 – Mar 2018
Biological Markers of System Burden in Symptomatic Knee OA: A Prospective Study
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAMS
Jun 2012 – Sep 2018
Assessing the Impact of Chronic Pain on Biological Measures of System Burden and Celluar Aging
Role: Principal Investigator
Funding: INTERNATIONAL ASSO FOR THE STUDY OF PAIN

Teaching Profile

Courses Taught
2020
PHC7918 Independent Study
2015
GMS7093 Introduction to Clinical and Translational Research
2012,2014
DEN5221 Oral Hlth Manage
2012
DEN5013 Found Professionalism

Contact Details

Phones:
Business:
(352) 294-5846
Emails:
Business:
ksibille@ufl.edu