Marco Pahor

Marco Pahor, M.D.

Professor & Director, Institute On Aging

Department: MD-AGING / GERIATRIC RESEARCH
Business Phone: (352) 294-5800
Business Email: mpahor@ufl.edu

About Marco Pahor

MARCO PAHOR, M.D., is the director of the University of Florida Institute on Aging .

Pahor is an internationally recognized expert on population-based studies, clinical trials and multidisciplinary translational research in the fields of aging, disability and cardiovascular disease.

An experienced geriatrician and epidemiologist, Pahor has an excellent publication record, having authored or co-authored more than 450 papers in leading peer-reviewed journals, which have been cited by other researchers more than 5,0000 times. He has an extensive portfolio of grants from the National Institutes of Health and other agencies, and is a leader in research and education, serving as director of the Claude D. Pepper Older Americans Independence Center and of the faculty mentoring program of the UF Clinical and Translational Science Institute.

Before coming to UF in 2005, Pahor held a number of positions at Wake Forest University, including director of the Sticht Center on Aging, deputy associate dean of the office of research and head of the section on gerontology and geriatrics. His previous academic appointments were at the University of Tennessee, the National Institutes of Health, the University of Florence, Italy, and the Catholic University in Rome, where he also earned his medical degree and completed residency.

Pahor is on the Physical Exercise Task Force and the Aging Clinical Trials Advisory Panel of the National Institute on Aging. He has served as an editor for a number of academic journals, including Aging, Clinical and Experimental Research, the Journal of the American Geriatrics Society, the Journal of Gerontology: Medical Sciences and the Journal of Nutrition, Health and Aging. He has served on numerous NIH grant and program review panels.

Publications

2021
Clinically Important Differences for Mobility Measures Derived from the Testosterone Trials.
Journal of the American Geriatrics Society. 69(2):517-523 [DOI] 10.1111/jgs.16942. [PMID] 33210287.
2021
Elevated IL-6 and CRP levels are associated with incident self-reported major mobility disability: A pooled analysis of older adults with slow gait speed.
The journals of gerontology. Series A, Biological sciences and medical sciences. [DOI] 10.1093/gerona/glab093. [PMID] 33822946.
2021
Machine Learning in Aging: An Example of Developing Prediction Models for Serious Fall Injury in Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 76(4):647-654 [DOI] 10.1093/gerona/glaa138. [PMID] 32498077.
2021
Quality of opioid prescribing in older adults with or without Alzheimer disease and related dementia.
Alzheimer's research & therapy. 13(1) [DOI] 10.1186/s13195-021-00818-3. [PMID] 33883028.
2021
Ratings of Perceived Exertion during Walking: Predicting Major Mobility Disability and Effect of Structured Physical Activity in Mobility-Limited Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. [DOI] 10.1093/gerona/glab036. [PMID] 33585918.
2021
Three-Year, Postintervention, Follow-up Comparison of Health Care Resource Utilization and Costs in the Lifestyle Interventions and Independence for Elders (LIFE) Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 76(2):272-276 [DOI] 10.1093/gerona/glaa088. [PMID] 32270182.
2021
Uncontrolled Pain and Risk for Depression and Behavioral Symptoms in Residents With Dementia.
Journal of the American Medical Directors Association. [DOI] 10.1016/j.jamda.2021.05.010. [PMID] 34089652.
2020
Agreement of Minimum Data Set 3.0 depression and behavioral symptoms with clinical diagnosis in a nursing home.
Aging & mental health. 1-6 [DOI] 10.1080/13607863.2020.1758921. [PMID] 32447973.
2020
Application of Cut-Points for Low Muscle Strength and Lean Mass in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society. 68(7):1445-1453 [DOI] 10.1111/jgs.16525. [PMID] 32633836.
2020
Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study.
Journal of clinical medicine. 9(11) [DOI] 10.3390/jcm9113757. [PMID] 33266358.
2020
Association of Fish Oil and Physical Activity on Mobility Disability in Older Adults.
Medicine and science in sports and exercise. 52(4):859-867 [DOI] 10.1249/MSS.0000000000002195. [PMID] 31688650.
2020
Comparative Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Response to a Physical Activity Intervention in Older Adults: Results From the Lifestyle Interventions and Independence for Elders Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 75(5):1010-1016 [DOI] 10.1093/gerona/glz120. [PMID] 31070702.
2020
Corrigendum: Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods.
Frontiers in aging neuroscience. 12 [DOI] 10.3389/fnagi.2020.00063. [PMID] 32194394.
2020
Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes: Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference.
The journals of gerontology. Series A, Biological sciences and medical sciences. 75(7):1317-1323 [DOI] 10.1093/gerona/glz081. [PMID] 30869772.
2020
Healthcare Utilization and Physical Functioning in Older Adults in the United States.
Journal of the American Geriatrics Society. 68(2):266-271 [DOI] 10.1111/jgs.16260. [PMID] 31755551.
2020
ICFSR Task Force Perspective on Biomarkers for Sarcopenia and Frailty.
The Journal of frailty & aging. 9(1):4-8 [DOI] 10.14283/jfa.2019.32. [PMID] 32150207.
2020
Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability.
Journal of the American Geriatrics Society. 68(4):872-881 [DOI] 10.1111/jgs.16365. [PMID] 32105353.
2020
Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study.
Journal of clinical medicine. 9(9) [DOI] 10.3390/jcm9092989. [PMID] 32947839.
2020
Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability.
Journal of the American Geriatrics Society. 68(3):619-624 [DOI] 10.1111/jgs.16274. [PMID] 31867713.
2020
Improving natural product research translation: From source to clinical trial.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34(1):41-65 [DOI] 10.1096/fj.201902143R. [PMID] 31914647.
2020
Innovations in Geroscience to enhance mobility in older adults.
Experimental gerontology. 142 [DOI] 10.1016/j.exger.2020.111123. [PMID] 33191210.
2020
Relationships Between Profiles of Physical Activity and Major Mobility Disability in the LIFE Study.
Journal of the American Geriatrics Society. 68(7):1476-1483 [DOI] 10.1111/jgs.16386. [PMID] 32196636.
2020
The relationship between interleukin-6 levels and physical performance in mobility-limited older adults with chronic low-grade inflammation: The ENRGISE Pilot study.
Archives of gerontology and geriatrics. 90 [DOI] 10.1016/j.archger.2020.104131. [PMID] 32554219.
2020
Trajectories of Short Physical Performance Battery Are Strongly Associated with Future Major Mobility Disability: Results from the LIFE Study.
Journal of clinical medicine. 9(8) [DOI] 10.3390/jcm9082332. [PMID] 32707877.
2019
A Case for Promoting Movement Medicine: Preventing Disability in the LIFE Randomized Controlled Trial.
The journals of gerontology. Series A, Biological sciences and medical sciences. 74(11):1821-1827 [DOI] 10.1093/gerona/glz050. [PMID] 30778518.
2019
Effect of Gastric Acid Suppressants on Response to a Physical Activity Intervention and Major Mobility Disability in Older Adults: Results from the Lifestyle Interventions for Elders (LIFE) Study.
Pharmacotherapy. 39(8):816-826 [DOI] 10.1002/phar.2299. [PMID] 31230397.
2019
Effect of Hospitalizations on Physical Activity Patterns in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society. 67(2):261-268 [DOI] 10.1111/jgs.15631. [PMID] 30452084.
2019
Effect of Losartan and Fish Oil on Plasma IL-6 and Mobility in Older Persons. The ENRGISE Pilot Randomized Clinical Trial.
The journals of gerontology. Series A, Biological sciences and medical sciences. 74(10):1612-1619 [DOI] 10.1093/gerona/gly277. [PMID] 30541065.
2019
Falls in Older Adults: Prevention, Mortality, and Costs.
JAMA. 321(21):2080-2081 [DOI] 10.1001/jama.2019.6569. [PMID] 31162553.
2019
Harvard HIV and Aging Workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research.
AIDS research and human retroviruses. 35(11-12):999-1012 [DOI] 10.1089/AID.2019.0130. [PMID] 31456412.
2019
Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods.
Frontiers in aging neuroscience. 11 [DOI] 10.3389/fnagi.2019.00358. [PMID] 31969814.
2019
Pain Assessments in MDS 3.0: Agreement with Vital Sign Pain Records of Nursing Home Residents.
Journal of the American Geriatrics Society. 67(11):2421-2422 [DOI] 10.1111/jgs.16122. [PMID] 31403708.
2019
Physical Activity and Performance Impact Long-term Quality of Life in Older Adults at Risk for Major Mobility Disability.
American journal of preventive medicine. 56(1):141-146 [DOI] 10.1016/j.amepre.2018.09.006. [PMID] 30573142.
2019
Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management.
The journal of nutrition, health & aging. 23(9):771-787 [DOI] 10.1007/s12603-019-1273-z. [PMID] 31641726.
2019
Prostate-Specific Antigen Levels During Testosterone Treatment of Hypogonadal Older Men: Data from a Controlled Trial.
The Journal of clinical endocrinology and metabolism. 104(12):6238-6246 [DOI] 10.1210/jc.2019-00806. [PMID] 31504596.
2019
The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study.
Nutrients. 11(7) [DOI] 10.3390/nu11071500. [PMID] 31262054.
2019
The Enabling Reduction of Low-Grade Inflammation in Seniors (ENRGISE) Pilot Study: Screening Methods and Recruitment Results.
The journals of gerontology. Series A, Biological sciences and medical sciences. 74(8):1296-1302 [DOI] 10.1093/gerona/gly204. [PMID] 30202946.
2018
A Comparison of Self-report Indices of Major Mobility Disability to Failure on the 400-m Walk Test: The LIFE Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(4):513-518 [DOI] 10.1093/gerona/glx153. [PMID] 28958023.
2018
Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults.
Frontiers in aging neuroscience. 10 [DOI] 10.3389/fnagi.2018.00341. [PMID] 30498440.
2018
Designing Drug Trials for Frailty: ICFSR Task Force 2018.
The Journal of frailty & aging. 7(3):150-154 [DOI] 10.14283/jfa.2018.20. [PMID] 30095144.
2018
Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
Journal of the American Geriatrics Society. 66(6):1172-1179 [DOI] 10.1111/jgs.15369. [PMID] 29637543.
2018
Effect of 24-month physical activity on cognitive frailty and the role of inflammation: the LIFE randomized clinical trial.
BMC medicine. 16(1) [DOI] 10.1186/s12916-018-1174-8. [PMID] 30352583.
2018
Effect of Physical Activity on Frailty.
Annals of internal medicine. 169(4) [DOI] 10.7326/L18-0243. [PMID] 30128516.
2018
Effect of Physical Activity on Frailty: Secondary Analysis of a Randomized Controlled Trial.
Annals of internal medicine. 168(5):309-316 [DOI] 10.7326/M16-2011. [PMID] 29310138.
2018
Effect of testosterone replacement on measures of mobility in older men with mobility limitation and low testosterone concentrations: secondary analyses of the Testosterone Trials.
The lancet. Diabetes & endocrinology. 6(11):879-890 [DOI] 10.1016/S2213-8587(18)30171-2. [PMID] 30366567.
2018
Evidence-based nutritional and pharmacological interventions targeting chronic low-grade inflammation in middle-age and older adults: A systematic review and meta-analysis.
Ageing research reviews. 46:42-59 [DOI] 10.1016/j.arr.2018.05.004. [PMID] 29803716.
2018
Gait Speed and Mobility Disability: Revisiting Meaningful Levels in Diverse Clinical Populations.
Journal of the American Geriatrics Society. 66(5):954-961 [DOI] 10.1111/jgs.15331. [PMID] 29608795.
2018
Implications of ICD-10 for Sarcopenia Clinical Practice and Clinical Trials: Report by the International Conference on Frailty and Sarcopenia Research Task Force.
The Journal of frailty & aging. 7(1):2-9 [DOI] 10.14283/jfa.2017.30. [PMID] 29412436.
2018
International Clinical Practice Guidelines for Sarcopenia (ICFSR): Screening, Diagnosis and Management.
The journal of nutrition, health & aging. 22(10):1148-1161 [DOI] 10.1007/s12603-018-1139-9. [PMID] 30498820.
2018
Lessons From the Testosterone Trials.
Endocrine reviews. 39(3):369-386 [DOI] 10.1210/er.2017-00234. [PMID] 29522088.
2018
Maintenance of Physical Function 1 Year After Exercise Intervention in At-Risk Older Adults: Follow-up From the LIFE Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(5):688-694 [DOI] 10.1093/gerona/glx231. [PMID] 29490012.
2018
Meta-analysis identifies mitochondrial DNA sequence variants associated with walking speed.
GeroScience. 40(5-6):497-511 [DOI] 10.1007/s11357-018-0043-x. [PMID] 30338417.
2018
Serious adverse events of older adults in nursing home and community intervention trials.
Contemporary clinical trials communications. 9:77-80 [DOI] 10.1016/j.conctc.2017.12.004. [PMID] 29696228.
2018
Social Participation Modifies the Effect of a Structured Physical Activity Program on Major Mobility Disability Among Older Adults: Results From the LIFE Study.
The journals of gerontology. Series B, Psychological sciences and social sciences. 73(8):1501-1513 [DOI] 10.1093/geronb/gbx051. [PMID] 28482106.
2018
The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) randomized controlled trial: Case finding, screening and characteristics of eligible participants.
Experimental gerontology. 113:48-57 [DOI] 10.1016/j.exger.2018.09.017. [PMID] 30261246.
2018
The Effect of Testosterone on Cardiovascular Biomarkers in the Testosterone Trials.
The Journal of clinical endocrinology and metabolism. 103(2):681-688 [DOI] 10.1210/jc.2017-02243. [PMID] 29253154.
2018
The exerkine apelin reverses age-associated sarcopenia.
Nature medicine. 24(9):1360-1371 [DOI] 10.1038/s41591-018-0131-6. [PMID] 30061698.
2018
The Relationship of Omega 3 Polyunsaturated Fatty Acids in Red Blood Cell Membranes with Cognitive Function and Brain Structure: A Review Focussed on Alzheimer’s Disease.
The journal of prevention of Alzheimer's disease. 5(1):78-84 [DOI] 10.14283/jpad.2017.19. [PMID] 29405237.
2017
A New Adaptive Home-based Exercise Technology among Older Adults Living in Nursing Home: A Pilot Study on Feasibility, Acceptability and Physical Performance.
The journal of nutrition, health & aging. 21(7):819-824 [DOI] 10.1007/s12603-016-0820-0. [PMID] 28717812.
2017
Association of Accelerometry-Measured Physical Activity and Cardiovascular Events in Mobility-Limited Older Adults: The LIFE (Lifestyle Interventions and Independence for Elders) Study.
Journal of the American Heart Association. 6(12) [DOI] 10.1161/JAHA.117.007215. [PMID] 29197830.
2017
Association of Testosterone Levels With Anemia in Older Men: A Controlled Clinical Trial.
JAMA internal medicine. 177(4):480-490 [DOI] 10.1001/jamainternmed.2016.9540. [PMID] 28241237.
2017
Device-Measured Physical Activity As a Predictor of Disability in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society. 65(10):2251-2256 [DOI] 10.1111/jgs.15037. [PMID] 28799216.
2017
Dose of physical activity, physical functioning and disability risk in mobility-limited older adults: Results from the LIFE study randomized trial.
PloS one. 12(8) [DOI] 10.1371/journal.pone.0182155. [PMID] 28820909.
2017
Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study.
Journal of the American Medical Directors Association. 18(4):312-319 [DOI] 10.1016/j.jamda.2016.10.001. [PMID] 27914851.
2017
Effect of Physical Activity on Self-Reported Disability in Older Adults: Results from the LIFE Study.
Journal of the American Geriatrics Society. 65(5):980-988 [DOI] 10.1111/jgs.14742. [PMID] 28168689.
2017
Effect of Physical Activity versus Health Education on Physical Function, Grip Strength and Mobility
Journal of the American Geriatrics Society.
2017
Effect of Physical Activity versus Health Education on Physical Function, Grip Strength and Mobility.
Journal of the American Geriatrics Society. 65(7):1427-1433 [DOI] 10.1111/jgs.14804. [PMID] 28221668.
2017
Effects of a Long-Term Physical Activity Program on Activity Patterns in Older Adults.
Medicine and science in sports and exercise. 49(11):2167-2175 [DOI] 10.1249/MSS.0000000000001340. [PMID] 29045323.
2017
Effects of Physical Activity Intervention on Physical and Cognitive Function in Sedentary Adults With and Without Diabetes.
The journals of gerontology. Series A, Biological sciences and medical sciences. 72(6):861-866 [DOI] 10.1093/gerona/glw179. [PMID] 27590629.
2017
ENabling Reduction of Low-grade Inflammation in SEniors Pilot Study: Concept, Rationale, and Design.
Journal of the American Geriatrics Society. 65(9):1961-1968 [DOI] 10.1111/jgs.14965. [PMID] 28734043.
2017
Exercise’s effect on mobility disability in older adults with and without obesity: The LIFE study randomized clinical trial.
Obesity (Silver Spring, Md.). 25(7):1199-1205 [DOI] 10.1002/oby.21860. [PMID] 28653499.
2017
Hippocampal Response to a 24-Month Physical Activity Intervention in Sedentary Older Adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 25(3):209-217 [DOI] 10.1016/j.jagp.2016.11.007. [PMID] 27986412.
2017
Impact of chemotherapy on medium-term physical function and activity of older breast cancer survivors, and associated biomarkers.
Journal of geriatric oncology. 8(1):69-75 [DOI] 10.1016/j.jgo.2016.09.004. [PMID] 27743848.
2017
Imputation of Gait Speed for Noncompleters in the 400-Meter Walk: Application to the Lifestyle Interventions for Elders Study.
Journal of the American Geriatrics Society. 65(12):2566-2571 [DOI] 10.1111/jgs.15078. [PMID] 28884789.
2017
Physical activity and exercise as countermeasures to physical frailty and sarcopenia.
Aging clinical and experimental research. 29(1):35-42 [DOI] 10.1007/s40520-016-0705-4. [PMID] 28181204.
2017
Predictors of Change in Physical Function in Older Adults in Response to Long-Term, Structured Physical Activity: The LIFE Study.
Archives of physical medicine and rehabilitation. 98(1):11-24.e3 [DOI] 10.1016/j.apmr.2016.07.019. [PMID] 27568165.
2017
Preserving older adults’ routine outdoor activities in contrasting neighborhood environments through a physical activity intervention.
Preventive medicine. 96:87-93 [DOI] 10.1016/j.ypmed.2016.12.049. [PMID] 28039068.
2017
Prognostic Value of Braden Activity Subscale for Mobility Status in Hospitalized Older Adults.
Journal of hospital medicine. 12(6):396-401 [DOI] 10.12788/jhm.2748. [PMID] 28574527.
2017
Rationale for a preliminary operational definition of physical frailty and sarcopenia in the SPRINTT trial.
Aging clinical and experimental research. 29(1):81-88 [DOI] 10.1007/s40520-016-0716-1. [PMID] 28188558.
2017
Resveratrol and exercise to treat functional limitations in late life: design of a randomized controlled trial.
Contemporary clinical trials communications. 6:58-63 [DOI] 10.1016/j.conctc.2017.03.002. [PMID] 28944303.
2017
Sarcopenia: an overview.
Aging clinical and experimental research. 29(1):11-17 [DOI] 10.1007/s40520-016-0704-5. [PMID] 28155183.
2017
Systemic inflammation, body composition, and physical performance in old community-dwellers.
Journal of cachexia, sarcopenia and muscle. 8(1):69-77 [DOI] 10.1002/jcsm.12134. [PMID] 27897412.
2017
Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment.
JAMA. 317(7):717-727 [DOI] 10.1001/jama.2016.21044. [PMID] 28241356.
2017
The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) randomized controlled trial: design and methods.
Aging clinical and experimental research. 29(1):89-100 [DOI] 10.1007/s40520-016-0715-2. [PMID] 28144914.
2017
The effect of intervening hospitalizations on the benefit of structured physical activity in promoting independent mobility among community-living older persons: secondary analysis of a randomized controlled trial.
BMC medicine. 15(1) [DOI] 10.1186/s12916-017-0824-6. [PMID] 28347337.
2016
Actigraphy features for predicting mobility disability in older adults
Physiological Measurement. 37:1813-1833
2016
Actigraphy features for predicting mobility disability in older adults.
Physiological measurement. 37(10):1813-1833 [PMID] 27653966.
View on: PubMed
2016
Antihypertensive Use and the Effect of a Physical Activity Intervention in the Prevention of Major Mobility Disability Among Older Adults: The LIFE Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 71(7):974-81 [DOI] 10.1093/gerona/glv222. [PMID] 26865496.
2016
Cardiovascular Events in a Physical Activity Intervention Compared With a Successful Aging Intervention: The LIFE Study Randomized Trial.
JAMA cardiology. 1(5):568-74 [DOI] 10.1001/jamacardio.2016.1324. [PMID] 27439082.
2016
Comparison of interactive voice response (IVR) with paper administration of instruments to assess functional status, sexual function, and quality of life in elderly men.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 25(4):811-21 [DOI] 10.1007/s11136-015-1133-1. [PMID] 26358063.
2016
Cost-effectiveness of the LIFE Physical Activity Intervention for Older Adults at Increased Risk for Mobility Disability.
The journals of gerontology. Series A, Biological sciences and medical sciences. 71(5):656-62 [DOI] 10.1093/gerona/glw001. [PMID] 26888433.
2016
Effect of a Long-Term Physical Activity Intervention on Resting Pulse Rate in Older Persons: Results from the Lifestyle Interventions and Independence for Elders Study.
Journal of the American Geriatrics Society. 64(12):2511-2516 [DOI] 10.1111/jgs.14380. [PMID] 27787876.
2016
Effect of Statin Use on Mobility Disability and Its Prevention in At-Risk Older Adults: the Life Study
Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 71(11):1519-1524 [DOI] 10.1093/gerona/glw057. [PMID] 26988662.
2016
Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized Trial.
Annals of internal medicine. 165(12):833-840 [DOI] 10.7326/M16-0529. [PMID] 27669457.
2016
Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized, Controlled Trial
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2016
Effect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study).
BMJ (Clinical research ed.). 352 [DOI] 10.1136/bmj.i245. [PMID] 26842425.
2016
Effect of Structured Physical Activity on Respiratory Outcomes in Sedentary Elderly Adults with Mobility Limitations.
Journal of the American Geriatrics Society. 64(3):501-9 [DOI] 10.1111/jgs.14013. [PMID] 27000324.
2016
Effects of Physical Activity Intervention on Physical and Cognitive Function in Sedentary Adults With and Without Diabetes
Journals of Gerontology Series A-Biological Sciences and Medical Sciences.
2016
Effects of Testosterone Treatment in Older Men
New England Journal of Medicine. 374(7):611-624 [DOI] 10.1056/NEJMoa1506119. [PMID] 26886521.
2016
Effects of Testosterone Treatment in Older Men.
The New England journal of medicine. 374(7):611-24 [DOI] 10.1056/NEJMoa1506119. [PMID] 26886521.
2016
Genetic Moderators of the Impact of Physical Activity on Depressive Symptoms.
The Journal of frailty & aging. 5(1):6-14 [DOI] 10.14283/jfa.2016.76. [PMID] 26980363.
2016
Hospitalizations During a Physical Activity Intervention in Older Adults at Risk of Mobility Disability: Analyses from the Lifestyle Interventions and Independence for Elders Randomized Clinical Trial.
Journal of the American Geriatrics Society. 64(5):933-43 [DOI] 10.1111/jgs.14114. [PMID] 27225353.
2016
Impact of moderate physical activity on the longitudinal trajectory of a cardiac specific biomarker of injury: Results from a randomized pilot study of exercise intervention.
American heart journal. 179:151-6 [DOI] 10.1016/j.ahj.2016.07.001. [PMID] 27595690.
2016
In-Hospital Mobility Variations Across Primary Diagnoses Among Older Adults.
Journal of the American Medical Directors Association. 17(5):465.e1-8 [DOI] 10.1016/j.jamda.2016.02.003. [PMID] 26971132.
2016
Neuropsychological Profile of “Cognitive Frailty” Subjects in MAPT Study.
The journal of prevention of Alzheimer's disease. 3(3):151-159 [PMID] 27547746.
View on: PubMed
2016
Socioeconomic differences in the benefits of structured physical activity compared with health education on the prevention of major mobility disability in older adults: the LIFE study.
Journal of epidemiology and community health. 70(9):930-3 [DOI] 10.1136/jech-2016-207321. [PMID] 27060177.
2016
Testosterone Treatment and Sexual Function in Older Men With Low Testosterone Levels
The Journal of clinical endocrinology and metabolism. 101(8):3096-3104 [DOI] 10.1210/jc.2016-1645. [PMID] 27355400.
2015
A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study
Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 70:216-222
2015
An observational study identifying obese subgroups among older adults at increased risk of mobility disability: do perceptions of the neighborhood environment matter?
The international journal of behavioral nutrition and physical activity. 12 [DOI] 10.1186/s12966-015-0322-1. [PMID] 26684894.
2015
Association of objectively measured physical activity with cardiovascular risk in mobility-limited older adults
. 4
2015
Association of objectively measured physical activity with cardiovascular risk in mobility-limited older adults.
Journal of the American Heart Association. 4(2) [DOI] 10.1161/JAHA.114.001288. [PMID] 25696062.
2015
Association of sex hormones with sexual function, vitality, and physical function of symptomatic older men with low testosterone levels at baseline in the testosterone trials.
The Journal of clinical endocrinology and metabolism. 100(3):1146-55 [DOI] 10.1210/jc.2014-3818. [PMID] 25548978.
2015
Correction: Light intensity physical activity and sedentary behavior in relation to body mass index and grip strength in older adults: cross-sectional findings from the Lifestyle Interventions and Independence for Elders (LIFE) study.
PloS one. 10(4) [DOI] 10.1371/journal.pone.0126063. [PMID] 25875330.
2015
Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial.
JAMA. 314(8):781-90 [DOI] 10.1001/jama.2015.9617. [PMID] 26305648.
2015
Effect of Structured Physical Activity on Sleep-Wake Behaviors in Sedentary Elderly Adults with Mobility Limitations.
Journal of the American Geriatrics Society. 63(7):1381-90 [DOI] 10.1111/jgs.13509. [PMID] 26115386.
2015
Effects of a One-Year Physical Activity Program on Serum C-Terminal Agrin Fragment (CAF) Concentrations among Mobility-Limited Older Adults.
The journal of nutrition, health & aging. 19(9):922-7 [DOI] 10.1007/s12603-015-0474-3. [PMID] 26482694.
2015
Frailty Clinical Phenotype: A Physical and Cognitive Point of View.
Nestle Nutrition Institute workshop series. 83:55-63 [DOI] 10.1159/000382061. [PMID] 26484671.
2015
Geriatrics Consults Associated With Improved Mortality and Disposition in Hospitalized Elders
Journal of the American Geriatrics Society. 63(1, SI)
2015
Increased inflammation but similar physical composition and function in older-aged, HIV-1 infected subjects.
BMC immunology. 16 [DOI] 10.1186/s12865-015-0106-z. [PMID] 26204934.
2015
Innovative Medicines Initiative: The SPRINT Project.
The Journal of frailty & aging. 4(4):207-8 [DOI] 10.14283/jfa.2015.69. [PMID] 27031019.
2015
Innovative Medicines Initiative: The SPRINTT Project.
The Journal of frailty & aging. 4(4):207-208 [PMID] 26693163.
View on: PubMed
2015
Light Intensity physical activity and sedentary behavior in relation to body mass index and grip strength in older adults: cross-sectional findings from the Lifestyle Interventions and Independence for Elders (LIFE) study.
PloS one. 10(2) [DOI] 10.1371/journal.pone.0116058. [PMID] 25647685.
2015
MOBILITY AND FUNCTIONAL OUTCOMES FOR SARCOPENIA TRIALS.
The Journal of frailty & aging. 4(3):123-4 [PMID] 26568949.
View on: PubMed
2015
Multi-modal intervention to reduce cardiovascular risk among hypertensive older adults: Design of a randomized clinical trial.
Contemporary clinical trials. 43:237-42 [DOI] 10.1016/j.cct.2015.06.019. [PMID] 26115878.
2015
Operationalization of the physical frailty & sarcopenia syndrome: rationale and clinical implementation.
Translational medicine @ UniSa. 13:29-32 [PMID] 27042430.
View on: PubMed
2015
PHARMACOLOGICAL INTERVENTIONS IN FRAILTY AND SARCOPENIA: REPORT BY THE INTERNATIONAL CONFERENCE ON FRAILTY AND SARCOPENIA RESEARCH TASK FORCE.
The Journal of frailty & aging. 4(3):114-120 [PMID] 26366378.
View on: PubMed
2015
Prevalence of metabolic syndrome and its association with physical capacity, disability, and self-rated health in Lifestyle Interventions and Independence for Elders Study participants
Journal of the American Geriatrics Society. 63:222-232
2015
Recruitment and Screening for the Testosterone Trials.
The journals of gerontology. Series A, Biological sciences and medical sciences. 70(9):1105-11 [DOI] 10.1093/gerona/glv031. [PMID] 25878029.
2015
Sedentary time is associated with the metabolic syndrome in older adults with mobility limitations–The LIFE Study.
Experimental gerontology. 70:32-6 [DOI] 10.1016/j.exger.2015.06.018. [PMID] 26130060.
2015
Serum Testosterone (T) Level Variability in T Gel-Treated Older Hypogonadal Men: Treatment Monitoring Implications
. JC20151542
2015
Serum Testosterone (T) Level Variability in T Gel-Treated Older Hypogonadal Men: Treatment Monitoring Implications.
The Journal of clinical endocrinology and metabolism. 100(9):3280-7 [DOI] 10.1210/JC.2015-1542. [PMID] 26120790.
2015
Successful aging: Advancing the science of physical independence in older adults.
Ageing research reviews. 24(Pt B):304-27 [DOI] 10.1016/j.arr.2015.09.005. [PMID] 26462882.
2015
The MAT-sf: identifying risk for major mobility disability.
The journals of gerontology. Series A, Biological sciences and medical sciences. 70(5):641-6 [DOI] 10.1093/gerona/glv003. [PMID] 25680917.
2014
Active muscle regeneration following eccentric contraction-induced injury is similar between healthy young and older adults.
Journal of applied physiology (Bethesda, Md. : 1985). 116(11):1481-90 [DOI] 10.1152/japplphysiol.01350.2012. [PMID] 23493365.
2014
Combined reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease in sedentary elders with functional limitations.
Journal of the American Medical Directors Association. 15(9):665-70 [DOI] 10.1016/j.jamda.2014.05.008. [PMID] 24973990.
2014
Effect of dietary restriction and exercise on lower extremity tissue compartments in obese, older women: a pilot study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 69(1):101-8 [DOI] 10.1093/gerona/gls337. [PMID] 23682155.
2014
Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial.
JAMA. 311(23):2387-96 [DOI] 10.1001/jama.2014.5616. [PMID] 24866862.
2014
Genetic influence on exercise-induced changes in physical function among mobility-limited older adults.
Physiological genomics. 46(5):149-58 [DOI] 10.1152/physiolgenomics.00169.2013. [PMID] 24423970.
2014
Mobility Impairment and Recovery During Hospitalization in Older Adults
Journal of the American Geriatrics Society. 62(1, SI)
2014
Patterns of circulating inflammatory biomarkers in older persons with varying levels of physical performance: a partial least squares-discriminant analysis approach.
Frontiers in medicine. 1 [DOI] 10.3389/fmed.2014.00027. [PMID] 25593902.
2014
Physical activity and resting pulse rate in older adults: findings from a randomized controlled trial.
American heart journal. 168(4):597-604 [DOI] 10.1016/j.ahj.2014.07.024. [PMID] 25262271.
2014
Respiratory Impairment and Dyspnea and Their Associations With Physical Inactivity and Mobility in Sedentary Community-Dwelling Older Persons
Journal of the American Geriatrics Society. 62(4):622-628 [DOI] 10.1111/jgs.12738. [PMID] 24635756.
2014
Sleep-wake disturbances in sedentary community-dwelling elderly adults with functional limitations.
Journal of the American Geriatrics Society. 62(6):1064-72 [DOI] 10.1111/jgs.12845. [PMID] 24889836.
2014
The effects of a long-term physical activity intervention on serum uric acid in older adults at risk for physical disability.
Journal of aging and physical activity. 22(1):25-33 [DOI] 10.1123/japa.2012-0018. [PMID] 23295313.
2014
The impact of sarcopenia on a physical activity intervention: the Lifestyle Interventions and Independence for Elders Pilot Study (LIFE-P).
The journal of nutrition, health & aging. 18(1):59-64 [DOI] 10.1007/s12603-013-0369-0. [PMID] 24402391.
2014
The LIFE Cognition Study: design and baseline characteristics.
Clinical interventions in aging. 9:1425-36 [DOI] 10.2147/CIA.S65381. [PMID] 25210447.
2014
The Testosterone Trials: Seven coordinated trials of testosterone treatment in elderly men.
Clinical trials (London, England). 11(3):362-375 [DOI] 10.1177/1740774514524032. [PMID] 24686158.
2013
Ankle brachial index values, leg symptoms, and functional performance among community-dwelling older men and women in the lifestyle interventions and independence for elders study
. 2(e000257)
2013
Ankle brachial index values, leg symptoms, and functional performance among community-dwelling older men and women in the lifestyle interventions and independence for elders study.
Journal of the American Heart Association. 2(6) [DOI] 10.1161/JAHA.113.000257. [PMID] 24222666.
2013
Cognitive frailty: frontiers and challenges.
The journal of nutrition, health & aging. 17(9):741-3 [DOI] 10.1007/s12603-013-0398-8. [PMID] 24154645.
2013
Designing pharmaceutical trials for sarcopenia in frail older adults: EU/US Task Force recommendations.
The journal of nutrition, health & aging. 17(7):612-8 [DOI] 10.1007/s12603-013-0362-7. [PMID] 23933872.
2013
How to design nutritional intervention trials to slow cognitive decline in apparently healthy populations and apply for efficacy claims: a statement from the International Academy on Nutrition and Aging Task Force.
The journal of nutrition, health & aging. 17(7):619-23 [DOI] 10.1007/s12603-013-0350-y. [PMID] 23933873.
2013
Lifestyle interventions and independence for elders study: recruitment and baseline characteristics.
The journals of gerontology. Series A, Biological sciences and medical sciences. 68(12):1549-58 [DOI] 10.1093/gerona/glt064. [PMID] 23716501.
2013
Lipid peroxidation and depressed mood in community-dwelling older men and women.
PloS one. 8(6) [DOI] 10.1371/journal.pone.0065406. [PMID] 23776478.
2013
Nonsteroidal anti-inflammatory drug (NSAID) use and sarcopenia in older people: results from the ilSIRENTE study.
Journal of the American Medical Directors Association. 14(8):626.e9-13 [DOI] 10.1016/j.jamda.2013.04.012. [PMID] 23747142.
2013
Promoting physical activity for elders with compromised function: the lifestyle interventions and independence for elders (LIFE) study physical activity intervention.
Clinical interventions in aging. 8:1119-31 [DOI] 10.2147/CIA.S49737. [PMID] 24049442.
2013
Snoring, daytime sleepiness, and incident cardiovascular disease in the health, aging, and body composition study.
Sleep. 36(11):1737-45 [DOI] 10.5665/sleep.3140. [PMID] 24179308.
2013
Study design of ASPirin in Reducing Events in the Elderly (ASPREE): a randomized, controlled trial
Contemporary Clinical Trials. 36:555-564
2013
Unhealthy lifestyles do not mediate the relationship between socioeconomic status and incident depressive symptoms: the Health ABC study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 21(7):664-74 [DOI] 10.1016/j.jagp.2013.01.004. [PMID] 23567402.
2012
Age-related differences in lower extremity tissue compartments and associations with physical function in older adults.
Experimental gerontology. 47(1):38-44 [DOI] 10.1016/j.exger.2011.10.001. [PMID] 22015325.
2012
Angiotensin-converting enzyme inhibitor use by older adults is associated with greater functional responses to exercise.
Journal of the American Geriatrics Society. 60(7):1244-52 [DOI] 10.1111/j.1532-5415.2012.04045.x. [PMID] 22726232.
2012
Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia.
Journal of cachexia, sarcopenia and muscle. 3(3):181-90 [DOI] 10.1007/s13539-012-0078-2. [PMID] 22865205.
2012
Design and Rationale for a Long-Term Study of Physical Activity in Older Adults
Gerontologist. 52
2012
Effects of a 12-month physical activity intervention on prevalence of metabolic syndrome in elderly men and women.
The journals of gerontology. Series A, Biological sciences and medical sciences. 67(4):417-24 [DOI] 10.1093/gerona/glr187. [PMID] 22024949.
2012
Making preventive medicine more personalized: implications for exercise-related research.
Preventive medicine. 55(1):34-6 [DOI] 10.1016/j.ypmed.2012.05.001. [PMID] 22588227.
2012
Making preventive medicine more personalized: implications for exercise-related research.
Preventive medicine. 55(1):34-6 [DOI] 10.1016/j.ypmed.2012.05.001. [PMID] 22588227.
2012
Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 67(6):671-6 [DOI] 10.1093/gerona/glr246. [PMID] 22389462.
2012
Prognosis of an abnormal one-leg balance in community-dwelling patients with Alzheimer’s disease: a 2-year prospective study in 686 patients of the REAL.FR study.
Journal of the American Medical Directors Association. 13(4):407.e1-6 [DOI] 10.1016/j.jamda.2011.11.003. [PMID] 22227074.
2012
Skeletal muscle apoptotic signaling predicts thigh muscle volume and gait speed in community-dwelling older persons: an exploratory study.
PloS one. 7(2) [DOI] 10.1371/journal.pone.0032829. [PMID] 22389725.
2012
The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals.
Aging cell. 11(5):801-9 [DOI] 10.1111/j.1474-9726.2012.00844.x. [PMID] 22681576.
2012
Total and abdominal adiposity are associated with inflammation in older adults using a factor analysis approach.
The journals of gerontology. Series A, Biological sciences and medical sciences. 67(10):1099-106 [DOI] 10.1093/gerona/gls077. [PMID] 22451470.
2011
An exploratory analysis of the effects of a weight loss plus exercise program on cellular quality control mechanisms in older overweight women.
Rejuvenation research. 14(3):315-24 [DOI] 10.1089/rej.2010.1132. [PMID] 21631380.
2011
Consideration of insurance reimbursement for physical activity and exercise programs for patients with diabetes.
JAMA. 305(17):1808-9 [DOI] 10.1001/jama.2011.572. [PMID] 21540427.
2011
Designing Phase II B trials in sarcopenia: the best target population.
The journal of nutrition, health & aging. 15(8):725-30 [PMID] 21968872.
View on: PubMed
2011
Effects of a weight loss plus exercise program on physical function in overweight, older women: a randomized controlled trial.
Clinical interventions in aging. 6:141-9 [DOI] 10.2147/CIA.S17001. [PMID] 21753869.
2011
Effects of a weight loss plus exercise program on physical functioning in overweight, older women: a randomized controlled trial
Clinical Interventions in Aging. 6:141-149
2011
Exercise Interventions and Glycemic Control in Patients With Diabetes Reply
Jama-Journal of the American Medical Association. 306:609-610
2011
Interleukin-6, C-reactive protein, and tumor necrosis factor-alpha as predictors of mortality in frail, community-living elderly individuals.
Journal of the American Geriatrics Society. 59(9):1679-85 [DOI] 10.1111/j.1532-5415.2011.03570.x. [PMID] 21883115.
2011
International working group on sarcopenia.
Journal of Nutrition Health & Aging. 15:450-455
2011
Metabolic Characterization of cold active Pseudomonas, Arthrobacter, Bacillus, and Flavobacterium spp. from Western Himalayas.
Indian journal of microbiology. 51(1):70-5 [DOI] 10.1007/s12088-011-0092-7. [PMID] 22282631.
2011
Muscle strength and BMI as predictors of major mobility disability in the Lifestyle Interventions and Independence for Elders pilot (LIFE-P).
The journals of gerontology. Series A, Biological sciences and medical sciences. 66(12):1376-83 [DOI] 10.1093/gerona/glr158. [PMID] 21975090.
2011
Reducing “iatrogenic disability” in the hospitalized frail elderly.
The journal of nutrition, health & aging. 15(8):645-60 [PMID] 21968859.
View on: PubMed
2011
Sarcopenia: biomarkers and imaging (International Conference on Sarcopenia research).
The journal of nutrition, health & aging. 15(10):834-46 [PMID] 22159770.
View on: PubMed
2011
Sarcopenia: designing phase IIB trials.
The journal of nutrition, health & aging. 15(6):450-5 [PMID] 21623466.
View on: PubMed
2011
The impact of behavioral intervention on obesity mediated declines in mobility function: implications for longevity.
Journal of aging research. 2011 [DOI] 10.4061/2011/392510. [PMID] 22013527.
2011
The Lifestyle Interventions and Independence for Elders Study: design and methods.
The journals of gerontology. Series A, Biological sciences and medical sciences. 66(11):1226-37 [DOI] 10.1093/gerona/glr123. [PMID] 21825283.
2011
Vitamin D hormone: a multitude of actions potentially influencing the physical function decline in older persons.
Geriatrics & gerontology international. 11(2):133-42 [DOI] 10.1111/j.1447-0594.2010.00668.x. [PMID] 21134097.
2010
ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.
Journal of the American Medical Directors Association. 11(1):26-32 [DOI] 10.1016/j.jamda.2009.09.014. [PMID] 20129212.
2010
Anorexia, physical function, and incident disability among the frail elderly population: results from the ilSIRENTE study.
Journal of the American Medical Directors Association. 11(4):268-74 [DOI] 10.1016/j.jamda.2009.12.088. [PMID] 20439047.
2010
Calorie restriction for optimal cardiovascular aging: the weight of evidence.
Current cardiovascular risk reports. 4(5):340-346 [PMID] 26388964.
View on: PubMed
2010
Disability, more than multimorbidity, was predictive of mortality among older persons aged 80 years and older.
Journal of clinical epidemiology. 63(7):752-9 [DOI] 10.1016/j.jclinepi.2009.09.007. [PMID] 20056387.
2010
Effect of Physical Activity On Hospitalization-Associated Functional Decline: the Life Pilot Study
Gerontologist. 50
2010
Effects of ACE-inhibition on IGF-1 and IGFBP-3 concentrations in older adults with high cardiovascular risk profile.
The journal of nutrition, health & aging. 14(6):457-60 [PMID] 20617288.
View on: PubMed
2010
Effects of exercise on mobility in obese and nonobese older adults.
Obesity (Silver Spring, Md.). 18(6):1168-75 [DOI] 10.1038/oby.2009.317. [PMID] 19834467.
2010
Evidence regarding the benefits of physical exercise.
Archives of internal medicine. 170(2):124-5 [DOI] 10.1001/archinternmed.2009.491. [PMID] 20101006.
2010
Executive control function, brain activation and white matter hyperintensities in older adults.
NeuroImage. 49(4):3436-42 [DOI] 10.1016/j.neuroimage.2009.11.019. [PMID] 19922803.
2010
Interaction of HDL cholesterol concentrations on the relationship between physical function and inflammation in community-dwelling older persons.
Age and ageing. 39(1):74-80 [DOI] 10.1093/ageing/afp194. [PMID] 19892744.
2010
Interleukin-6, C-Reactive Protein, Tumor Necrosis Factor-Alpha as Predictors of Mortality in Frail, Community-Living Elderly Individuals.
Journal of the American Geriatrics Society. 58
2010
Late-life depressed mood and weight change contribute to the risk of each other.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 18(3):236-44 [DOI] 10.1097/JGP.0b013e3181c65837. [PMID] 20224519.
2010
Long-term physical activity and inflammatory biomarkers in older adults.
Medicine and science in sports and exercise. 42(12):2189-96 [DOI] 10.1249/MSS.0b013e3181e3ac80. [PMID] 20421832.
2010
Midarm muscle circumference, physical performance and mortality: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study).
Clinical nutrition (Edinburgh, Scotland). 29(4):441-7 [DOI] 10.1016/j.clnu.2009.12.006. [PMID] 20116909.
2010
Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy.
Ageing research reviews. 9(4):369-83 [DOI] 10.1016/j.arr.2010.04.004. [PMID] 20438881.
2010
Multiple pathways to the same end: mechanisms of myonuclear apoptosis in sarcopenia of aging.
TheScientificWorldJournal. 10:340-9 [DOI] 10.1100/tsw.2010.27. [PMID] 20191247.
2010
Myeloperoxidase levels and mortality in frail community-living elderly individuals.
The journals of gerontology. Series A, Biological sciences and medical sciences. 65(4):369-76 [DOI] 10.1093/gerona/glp183. [PMID] 20064836.
2010
Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions.
Cardiovascular therapeutics. 28(5):e72-91 [DOI] 10.1111/j.1755-5922.2010.00171.x. [PMID] 20626406.
2010
Psychomotor speed and functional brain MRI 2 years after completing a physical activity treatment.
The journals of gerontology. Series A, Biological sciences and medical sciences. 65(6):639-47 [DOI] 10.1093/gerona/glq038. [PMID] 20348185.
2009
A cost analysis of a physical activity intervention for older adults.
Journal of physical activity & health. 6(6):767-74 [PMID] 20101920.
View on: PubMed
2009
Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study.
Journal of the American Geriatrics Society. 57(2):251-9 [DOI] 10.1111/j.1532-5415.2008.02126.x. [PMID] 19207142.
2009
Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.
American heart journal. 157(2):334.e1-8 [DOI] 10.1016/j.ahj.2008.10.026. [PMID] 19185642.
2009
Association Between Inflammatory Components and Physical Function in the Health, Aging, and Body Composition Study: a Principal Component Analysis Approach
Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 64(5):581-589 [DOI] 10.1093/gerona/glp005. [PMID] 19228783.
2009
C-reactive protein and lipid parameters in older persons aged 80 years and older.
The journal of nutrition, health & aging. 13(7):587-93 [PMID] 19621193.
View on: PubMed
2009
Carla Task Force on Sarcopenia: propositions for clinical trials.
The journal of nutrition, health & aging. 13(8):700-7 [PMID] 19657553.
View on: PubMed
2009
Changes in cognitive function in a randomized trial of physical activity: results of the lifestyle interventions and independence for elders pilot study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 64(6):688-94 [DOI] 10.1093/gerona/glp014. [PMID] 19244157.
2009
Chronic inflammation is associated with low physical function in older adults across multiple comorbidities.
The journals of gerontology. Series A, Biological sciences and medical sciences. 64(4):455-61 [DOI] 10.1093/gerona/gln038. [PMID] 19196644.
2009
Daily pain and functional decline among old-old adults living in the community: results from the ilSIRENTE Study.
Journal of pain and symptom management. 38(3):350-7 [DOI] 10.1016/j.jpainsymman.2008.10.005. [PMID] 19359134.
2009
Effects of Lifestyle Modification On Muscle Strength and Quality in Obese Older Adults
Gerontologist. 49
2009
Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength.
The journals of gerontology. Series A, Biological sciences and medical sciences. 64(11):1183-9 [DOI] 10.1093/gerona/glp097. [PMID] 19622801.
2009
Indications, labeling, and outcomes assessment for drugs aimed at improving functional status in older persons: a conversation between aging researchers and FDA regulators.
The journals of gerontology. Series A, Biological sciences and medical sciences. 64(4):487-91 [DOI] 10.1093/gerona/gln042. [PMID] 19270182.
2009
Inflammation and race and gender differences in computerized tomography-measured adipose depots.
Obesity (Silver Spring, Md.). 17(5):1062-9 [DOI] 10.1038/oby.2008.627. [PMID] 19165157.
2009
Metabolic syndrome and physical decline in older persons: results from the Health, Aging And Body Composition Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 64(1):96-102 [DOI] 10.1093/gerona/gln005. [PMID] 19164274.
2009
Moderate alcohol intake and risk of functional decline: the Health, Aging, and Body Composition study.
Journal of the American Geriatrics Society. 57(10):1767-75 [DOI] 10.1111/j.1532-5415.2009.02479.x. [PMID] 19737328.
2009
Physical activity and maintaining physical function in older adults.
British journal of sports medicine. 43(1):28-31 [DOI] 10.1136/bjsm.2008.053736. [PMID] 18927164.
2009
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
Nature. 460(7253):392-5 [DOI] 10.1038/nature08221. [PMID] 19587680.
2009
Sarcopenia: clinical evaluation, biological markers and other evaluation tools.
The journal of nutrition, health & aging. 13(8):724-8 [PMID] 19657557.
View on: PubMed
2009
Self-assessed health status, walking speed and mortality in older Mexican-Americans.
Gerontology. 55(2):194-201 [DOI] 10.1159/000174824. [PMID] 19018125.
2009
Skeletal muscle and mortality results from the InCHIANTI Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 64(3):377-84 [DOI] 10.1093/gerona/gln031. [PMID] 19181709.
2009
Stopping to rest during a 400-meter walk and incident mobility disability in older persons with functional limitations.
Journal of the American Geriatrics Society. 57(2):260-5 [DOI] 10.1111/j.1532-5415.2008.02097.x. [PMID] 19170785.
2009
The Ace I/D Genotype and Improvement in 400-Meter Walk Performance With Exercise Training in the Lifestyle Intervention and Independence for Elders Pilot (Life-P)
Journal of the American Geriatrics Society. 57
2009
What is a meaningful change in physical performance? Findings from a clinical trial in older adults (the LIFE-P study).
The journal of nutrition, health & aging. 13(6):538-44 [PMID] 19536422.
View on: PubMed
2008
A Cost Analysis of a Physical Activity Intervention for Older Adults
Annals of Behavioral Medicine. 35
2008
Association Between Changes in Inflammation and Risk for Mobility Disability
Gerontologist. 48
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Gerontologist. 48:491-492
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2008
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Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 63:160-164
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Physical function, physical activity and recent falls. Results from the “Invecchiamento e Longevita nel Sirente (ilSIRENTE)” Study
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Stopping To Rest During a 400-Meter Walk and Incident Mobility Disability in Older Persons With Functional Limitations
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The Burning Issue of Inflammaging
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The Magnitude and Meaning of Performance Change in a Clinical Trial: the Life-P Study
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Designing clinical trials of interventions for mobility disability: results from the lifestyle interventions and independence for elders pilot (LIFE-P) trial.
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Designing clinical trials of interventions for mobility disability: results from the lifestyle interventions and independence for elders pilot (LIFE-P) trial.
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Diabetes mellitus, glycemic control, and incident depressive symptoms among 70- to 79-year-old persons: the health, aging, and body composition study.
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HDL-cholesterol and physical performance: results from the ageing and longevity study in the sirente geographic area (ilSIRENTE Study).
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The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers
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Association of Visceral Adipose Tissue With Incident Myocardial Infarction in Older Men and Women: The Health, Aging and Body Composition Study
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Bone density and hemoglobin levels in older persons: results from the InCHIANTI study.
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Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study.
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Measures of physical performance and risk for progressive and catastrophic disability: results from the Women’s Health and Aging Study.
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Physical function and its response to exercise: associations with cytokine gene variation in older adults with knee osteoarthritis.
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Prognostic value of usual gait speed in well-functioning older people–results from the Health, Aging and Body Composition Study.
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Sarcopenia, obesity and inflammation – Results from theTrial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study
American Journal of Clinical Nutrition. 82:428-434
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The ilSIRENTE study: a prospective cohort study on persons aged 80 years and older living in a mountain community of Central Italy.
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The lifestyle interventions and independence for elders (LIFE) pilot study: design and methods.
Contemporary clinical trials. 26(2):141-54 [PMID] 15837437.
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Anemia is associated with disability and decreased physical performance and muscle strength in the elderly.
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Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged rats.
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Antihypertensive medications and differences in muscle mass in older persons: the Health, Aging and Body Composition Study.
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Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) study.
The American journal of clinical nutrition. 79(2):289-94 [PMID] 14749236.
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Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition Study.
American journal of epidemiology. 160(8):741-9 [PMID] 15466496.
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Designing randomized controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report
Journal of the American Geriatrics Society. 52:625-634
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Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial.
The American journal of clinical nutrition. 79(4):544-51 [PMID] 15051595.
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2004
Dietary-induced weight loss, exercise and chronic inflammation in older, obese adults: A randomized controlled clinical trial
American Journal of Clinical Nutrition. 79:544-551
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Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial.
Arthritis and rheumatism. 50(5):1501-10 [PMID] 15146420.
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Hemoglobin levels and skeletal muscle: results from the InCHIANTI study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 59(3):249-54 [PMID] 15031309.
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Inflammatory markers and incident mobility limitation in the elderly.
Journal of the American Geriatrics Society. 52(7):1105-13 [PMID] 15209648.
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Inflammatory markers and physical function among older adults with knee osteoarthritis.
The Journal of rheumatology. 31(10):2027-31 [PMID] 15468370.
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Inflammatory markers and physical performance in older persons: the InCHIANTI study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 59(3):242-8 [PMID] 15031308.
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Muscle strength in obese elderly women: effect of recreational physical activity in a cross-sectional study.
The American journal of clinical nutrition. 79(4):552-7 [PMID] 15051596.
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Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study.
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Relationship of alcohol intake with inflammatory markers and plasminogen activator inhibitor-1 in well-functioning older adults: the Health, Aging, and Body Composition study.
Circulation. 109(5):607-12 [PMID] 14769682.
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Reliability of the 400-m usual-pace walk test as an assessment of mobility limitation in older adults.
Journal of the American Geriatrics Society. 52(6):972-6 [PMID] 15161464.
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Use of angiotensin-converting enzyme inhibitors in elderly people with heart failure: prevalence and outcomes.
The journals of gerontology. Series A, Biological sciences and medical sciences. 59(7):716-21 [PMID] 15304537.
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Anemia and decline in physical performance among older persons.
The American journal of medicine. 115(2):104-10 [PMID] 12893395.
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Association between ACE inhibitors use and headache caused by nitrates among hypertensive patients: results from the Italian group of pharmacoepidemiology in the elderly (GIFA).
Cephalalgia : an international journal of headache. 23(9):901-6 [PMID] 14616932.
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Beta-blockers after acute myocardial infarction in elderly patients with diabetes mellitus: time to reassess.
Drugs & aging. 20(1):13-22 [PMID] 12513113.
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Depression and adverse drug reactions among hospitalized older adults.
Archives of internal medicine. 163(3):301-5 [PMID] 12578510.
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Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis.
JAMA. 289(19):2534-44 [PMID] 12759325.
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Impact of hospitalization on blood pressure control in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA).
Pharmacotherapy. 23(2):240-7 [PMID] 12587813.
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Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study).
The American journal of cardiology. 92(5):522-8 [PMID] 12943870.
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Inflammatory markers and cognition in well-functioning African-American and white elders.
Neurology. 61(1):76-80 [PMID] 12847160.
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Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study.
Biological psychiatry. 54(5):566-72 [PMID] 12946885.
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Inflammatory markers and onset of cardiovascular events: results from the Health ABC study.
Circulation. 108(19):2317-22 [PMID] 14568895.
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One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women.
Journal of applied physiology (Bethesda, Md. : 1985). 94(6):2368-74 [PMID] 12598481.
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Sexual satisfaction and risk of disability in older women.
The Journal of clinical psychiatry. 64(10):1177-82 [PMID] 14658965.
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The effects of cognitive impairment on mortality among hospitalized patients with heart failure.
The American journal of medicine. 115(2):97-103 [PMID] 12893394.
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ACE inhibitors use and changes in muscle strength and physical performance in older women
Lancet. 359:926-930
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African-American ethnicity in epidemiological studies of calcium antagonists in relation to cancer.
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Blood pressure and decline in kidney function: findings from the Systolic Hypertension in the Elderly Program (SHEP).
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Body mass index, weight change, and death in older adults: the systolic hypertension in the elderly program.
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Change in physical performance over time in older women: the Women’s Health and Aging Study.
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Evaluation and correction for a ‘training effect’ in the cognitive assessment of older adults.
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Exercise and depressive symptoms: a comparison of aerobic and resistance exercise effects on emotional and physical function in older persons with high and low depressive symptomatology.
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Fosinopril versus amlodipine comparative treatments study: a randomized trial to assess effects on plasminogen activator inhibitor-1.
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Obese, older adults with knee osteoarthritis: weight loss, exercise, and quality of life.
Health psychology : official journal of the Division of Health Psychology, American Psychological Association. 21(5):419-26 [PMID] 12211508.
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Physical performance and longevity in aged rats.
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Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study.
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Trends in prescribing ACE-inhibitors for congestive heart failure in elderly people.
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An animal model of physical disability: a preclinical strategy for improving assessment and intervention
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Aortic stiffness is associated with visceral adiposity in older adults enrolled in the study of health, aging, and body composition.
Hypertension (Dallas, Tex. : 1979). 38(3):429-33 [PMID] 11566917.
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Assessment of physical function in aging rodents: a strategy for improving preclinical testing.
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Clinical Implications of Recent Findings from the Antihypertensive and Lipid-Lowering Treatment To Prevent Heart Attack Trial (ALLHAT) and Other Studies of Hypertension.
Annals of internal medicine. 135(12):1074-8 [PMID] 11747386.
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Dementia and disability outcomes in large hypertension trials: lessons learned from the systolic hypertension in the elderly program (SHEP) trial.
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Financial difficulty in acquiring food among elderly disabled women: results from the Women’s Health and Aging Study.
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Hypotension and cognitive impairment: Selective association in patients with heart failure.
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Predicting length of stay of older patients with exacerbated chronic obstructive pulmonary disease.
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Reasons prompting digitalis therapy in the acute care hospital.
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