Selected Peer-reviewed Publications (Selected from over 300 peer-reviewed publications)


Buford TW, Manini TM, Hsu FC, Cesari M, Anton SD, Nayfield S, Stafford RS, Church TS, Pahor M, Carter CS. Angiotensin-converting enzyme inhibitor use by older adults is associated with greater functional responses to exercise. J Am Geriatr Soc. 2012 Jul;60(7):1244-52. doi: 10.1111/j.1532-5415.2012.04045.x. Epub 2012 Jun 21. PubMed PMID: 22726232.


Joseph AM, Adhihetty PJ, Buford TW, Wohlgemuth SE, Lees HA, Nguyen LM, Aranda JM, Sandesara BD, Pahor M, Manini TM, Marzetti E, Leeuwenburgh C. The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals. Aging Cell. 2012 Jun 8. doi: 10.1111/j.1474-9726.2012.00844.x. [Epub ahead of print] PubMed PMID: 22681576.


Buford TW, Pahor M. Making preventive medicine more personalized: Implications for exercise-related research. Prev Med. 2012 Jul;55(1):34-6. Epub 2012 May 14. PubMed PMID: 22588227.


Groffen DA, Koster A, Bosma H, van den Akker M, Kempen GI, van Eijk JT, van Gool CH, Penninx BW, Harris TB, Rubin SM, Pahor M, Schulz R, Simonsick EM, Perry SE, Ayonayon HN, Kritchevsky SB; for the Health ABC study. Unhealthy Lifestyles Do Not Mediate the Relationship Between Socioeconomic Status and Incident Depressive Symptoms: The Health ABC study. Am J Geriatr Psychiatry. 2012 Apr 16. [Epub ahead of print] PubMed PMID: 22510729.


Brinkley TE, Hsu FC, Beavers KM, Church TS, Goodpaster BH, Stafford RS, Pahor M, Kritchevsky SB, Nicklas BJ. Total and Abdominal Adiposity Are Associated With Inflammation in Older Adults Using a Factor Analysis Approach. J Gerontol A Biol Sci Med Sci. 2012 Mar 26. [Epub ahead of print] PubMed PMID: 22451470.


Marzetti E, Lees HA, Manini TM, Buford TW, Aranda JM Jr, Calvani R, Capuani G, Marsiske M, Lott DJ, Vandenborne K, Bernabei R, Pahor M, Leeuwenburgh C, Wohlgemuth SE. Skeletal muscle apoptotic signaling predicts thigh muscle volume and gait speed in community-dwelling older persons: an exploratory study. PLoS One. 2012;7(2):e32829. Epub 2012 Feb 28. PubMed PMID: 22389725; PubMed Central PMCID: PMC3289676.


Cesari M, Kritchevsky SB, Nicklas B, Kanaya AM, Patrignani P, Tacconelli S, Tranah GJ, Tognoni G, Harris TB, Incalzi RA, Newman AB, Pahor M; Health ABC study. Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study. J Gerontol A Biol Sci Med Sci. 2012 Jun;67(6):671-6. Epub 2012 Mar 1. PubMed PMID: 22389462; PubMed Central PMCID: PMC3348494.


Sourdet S, Van Kan GA, Soto ME, Houles M, Cantet C, Nourhashemi F, Vellas B, Pahor M, Rolland Y. Prognosis of an abnormal one-leg balance in community-dwelling patients with Alzheimer’s disease: a 2-year prospective study in 686 patients of the REAL.FR study. J Am Med Dir Assoc. 2012 May;13(4):407.e1-6. Epub 2012 Jan 9. PubMed PMID: 22227074.


Wang X, Hsu FC, Isom S, Walkup MP, Kritchevsky SB, Goodpaster BH, Church TS, Pahor M, Stafford RS, Nicklas BJ. Effects of a 12-month physical activity intervention on prevalence of metabolic syndrome in elderly men and women. J Gerontol A Biol Sci Med Sci. 2012 Apr;67(4):417-24. Epub 2011 Oct 24. PubMed PMID: 22024949; PubMed Central PMCID: PMC3309873.


Buford TW, Lott DJ, Marzetti E, Wohlgemuth SE, Vandenborne K, Pahor M, Leeuwenburgh C, Manini TM. Age-related differences in lower extremity tissue compartments and associations with physical function in older adults. Exp Gerontol. 2012 Jan;47(1):38-44. Epub 2011 Oct 12. PubMed PMID: 22015325; PubMed Central PMCID: PMC3245356.


Nocera J, Buford TW, Manini TM, Naugle K, Leeuwenburgh C, Pahor M, Perri MG, Anton SD. The impact of behavioral intervention on obesity mediated declines in mobility function: implications for longevity. J Aging Res. 2011;2011:392510. Epub 2011 Oct 16. PubMed PMID: 22013527; PubMed Central PMCID: PMC3195552.


Marsh AP, Rejeski WJ, Espeland MA, Miller ME, Church TS, Fielding RA, Gill TM, Guralnik JM, Newman AB, Pahor M; LIFE Study Investigators. Muscle strength and BMI as predictors of major mobility disability in the Lifestyle Interventions and Independence for Elders pilot (LIFE-P). J Gerontol A Biol Sci Med Sci. 2011 Dec;66(12):1376-83. Epub 2011 Oct 5. PubMed PMID: 21975090; PubMed Central PMCID: PMC3210962.


Giovannini S, Onder G, Liperoti R, Russo A, Carter C, Capoluongo E, Pahor M, Bernabei R, Landi F. Interleukin-6, C-reactive protein, and tumor necrosis factor-alpha as predictors of mortality in frail, community-living elderly individuals. J Am Geriatr Soc. 2011 Sep;59(9):1679-85. doi: 10.1111/j.1532-5415.2011.03570.x. Epub 2011 Aug 24. PubMed PMID: 21883115.


Fielding RA, Rejeski WJ, Blair S, Church T, Espeland MA, Gill TM, Guralnik JM, Hsu FC, Katula J, King AC, Kritchevsky SB, McDermott MM, Miller ME, Nayfield S, Newman AB, Williamson JD, Bonds D, Romashkan S, Hadley E, Pahor M; LIFE Research Group. The Lifestyle Interventions and Independence for Elders Study: design and methods. J Gerontol A Biol Sci Med Sci. 2011 Nov;66(11):1226-37. Epub 2011 Aug 8. PubMed PMID: 21825283; PubMed Central PMCID: PMC3193523.


Anton SD, Manini TM, Milsom VA, Dubyak P, Cesari M, Cheng J, Daniels MJ, Marsiske M, Pahor M, Leeuwenburgh C, Perri MG. Effects of a weight loss plus exercise program on physical function in overweight, older women: a randomized controlled trial. Clin Interv Aging. 2011;6:141-9. doi: 10.2147/CIA.S17001. Epub 2011 Jun 15. PubMed PMID: 21753869; PubMed Central PMCID: PMC3131984.


Wohlgemuth SE, Lees HA, Marzetti E, Manini TM, Aranda JM, Daniels MJ, Pahor M, Perri MG, Leeuwenburgh C, Anton SD. An exploratory analysis of the effects of a weight loss plus exercise program on cellular quality control mechanisms in older overweight women. Rejuvenation Res. 2011 Jun;14(3):315-24. Epub 2011 Jun 1. PubMed PMID: 21631380; PubMed Central PMCID: PMC3136739.


Chumlea WC, Cesari M, Evans WJ, Ferrucci L, Fielding RA, Pahor M, Studenski S, Vellas B; International Working Group on Sarcopenia Task Force Members. Sarcopenia: designing phase IIB trials. J Nutr Health Aging. 2011 Jun;15(6):450-5. PubMed PMID: 21623466; PubMed Central PMCID: PMC3367322.


Pahor M. Consideration of insurance reimbursement for physical activity and exercise programs for patients with diabetes. JAMA. 2011 May 4;305(17):1808-9. PubMed PMID: 21540427.


Cesari M, Incalzi RA, Zamboni V, Pahor M. Vitamin D hormone: a multitude of actions potentially influencing the physical function decline in older persons. Geriatr Gerontol Int. 2011 Apr;11(2):133-42. doi: 10.1111/j.1447-0594.2010.00668.x. Epub 2010 Dec 6. Review. PubMed PMID: 21134097.


Cesari M, Pahor M, Incalzi RA. Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions. Cardiovasc Ther. 2010 Oct;28(5):e72-91. doi: 10.1111/j.1755-5922.2010.00171.x. Epub 2010 Jul 7. Review. PubMed PMID: 20626406; PubMed Central PMCID: PMC2958211.


Landi F, Russo A, Liperoti R, Tosato M, Barillaro C, Pahor M, Bernabei R, Onder G. Anorexia, physical function, and incident disability among the frail elderly population: results from the ilSIRENTE study. J Am Med Dir Assoc. 2010 May;11(4):268-74. Epub 2010 Apr 3. PubMed PMID: 20439047.


Buford TW, Anton SD, Judge AR, Marzetti E, Wohlgemuth SE, Carter CS, Leeuwenburgh C, Pahor M, Manini TM. Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy. Ageing Res Rev. 2010 Oct;9(4):369-83. Epub 2010 May 14. Review. PubMed PMID: 20438881.


Beavers KM, Hsu FC, Isom S, Kritchevsky SB, Church T, Goodpaster B, Pahor M, Nicklas BJ. Long-term physical activity and inflammatory biomarkers in older adults. Med Sci Sports Exerc. 2010 Dec;42(12):2189-96. PubMed PMID: 20421832; PubMed Central PMCID: PMC2964389.


Rosano C, Venkatraman VK, Guralnik J, Newman AB, Glynn NW, Launer L, Taylor CA, Williamson J, Studenski S, Pahor M, Aizenstein H. Psychomotor speed and functional brain MRI 2 years after completing a physical activity treatment. J Gerontol A Biol Sci Med Sci. 2010 Jun;65(6):639-47. Epub 2010 Mar 26. PubMed PMID: 20348185; PubMed Central PMCID: PMC2869531.


Koster A, van Gool CH, Kempen GI, Penninx BW, Lee JS, Rubin SM, Tylavsky FA, Yaffe K, Newman AB, Harris TB, Pahor M, Ayonayon HN, van Eijk JT, Kritchevsky SB; Health ABC Study. Late-life depressed mood and weight change contribute to the risk of each other. Am J Geriatr Psychiatry. 2010 Mar;18(3):236-44. PubMed PMID: 20224519; PubMed Central PMCID: PMC2838199.


Marzetti E, Privitera G, Simili V, Wohlgemuth SE, Aulisa L, Pahor M, Leeuwenburgh C. Multiple pathways to the same end: mechanisms of myonuclear apoptosis in sarcopenia of aging. ScientificWorldJournal. 2010 Feb 19;10:340-9. Review. PubMed PMID: 20191247.


Cesari M, Pedone C, Incalzi RA, Pahor M. ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. J Am Med Dir Assoc. 2010 Jan;11(1):26-32. Epub 2009 Nov 25. PubMed PMID: 20129212; PubMed Central PMCID: PMC2818218.


Landi F, Russo A, Liperoti R, Pahor M, Tosato M, Capoluongo E, Bernabei R, Onder G. Midarm muscle circumference, physical performance and mortality: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study). Clin Nutr. 2010 Aug;29(4):441-7. Epub 2010 Feb 8. PubMed PMID: 20116909.


Groessl EJ, Kaplan RM, Blair SN, Rejeski WJ, Katula JA, King AC, Fielding RA, Glynn NW, Pahor M. A cost analysis of a physical activity intervention for older adults. J Phys Act Health. 2009 Nov;6(6):767-74. PubMed PMID: 20101920; PubMed Central PMCID: PMC3091594.


Williamson J, Pahor M. Evidence regarding the benefits of physical exercise. Arch Intern Med. 2010 Jan 25;170(2):124-5. PubMed PMID: 20101006.


Giovannini S, Onder G, Leeuwenburgh C, Carter C, Marzetti E, Russo A, Capoluongo E, Pahor M, Bernabei R, Landi F. Myeloperoxidase levels and mortality in frail community-living elderly individuals. J Gerontol A Biol Sci Med Sci. 2010 Apr;65(4):369-76. Epub 2010 Jan 11. PubMed PMID: 20064836.


Landi F, Liperoti R, Russo A, Capoluongo E, Barillaro C, Pahor M, Bernabei R, Onder G. Disability, more than multimorbidity, was predictive of mortality among older persons aged 80 years and older. J Clin Epidemiol. 2010 Jul;63(7):752-9. Epub 2010 Jan 8. PubMed PMID: 20056387.


Venkatraman VK, Aizenstein H, Guralnik J, Newman AB, Glynn NW, Taylor C, Studenski S, Launer L, Pahor M, Williamson J, Rosano C. Executive control function, brain activation and white matter hyperintensities in older adults. Neuroimage. 2010 Feb 15;49(4):3436-42. Epub 2009 Nov 14. Erratum in: Neuroimage. 2010 May 1;50(4):1711. PubMed PMID: 19922803; PubMed Central PMCID: PMC2818521.


Cesari M, Marzetti E, Laudisio A, Antonica L, Pahor M, Bernabei R, ZuccalĂ  G. Interaction of HDL cholesterol concentrations on the relationship between physical function and inflammation in community-dwelling older persons. Age Ageing. 2010 Jan;39(1):74-80. Epub 2009 Nov 5. PubMed PMID: 19892744; PubMed Central PMCID: PMC2800252.


Manini TM, Newman AB, Fielding R, Blair SN, Perri MG, Anton SD, Goodpaster BC, Katula JA, Rejeski WJ, Kritchevsky SB, Hsu FC, Pahor M, King AC; LIFE Research Group. Effects of exercise on mobility in obese and nonobese older adults. Obesity (Silver Spring). 2010 Jun;18(6):1168-75. Epub 2009 Oct 15. Erratum in: Obesity (Silver Spring).2011 May;19(5):1106. King, Abby C [added]. PubMed PMID: 19834467; PubMed Central PMCID: PMC3114403.


Maraldi C, Harris TB, Newman AB, Kritchevsky SB, Pahor M, Koster A, Satterfield S, Ayonayon HN, Fellin R, Volpato S; Health ABC study. Moderate alcohol intake and risk of functional decline: the Health, Aging, and Body Composition study. J Am Geriatr Soc. 2009 Oct;57(10):1767-75. Epub 2009 Sep 8. PubMed PMID: 19737328; PubMed Central PMCID: PMC3149890.


Schaap LA, Pluijm SM, Deeg DJ, Harris TB, Kritchevsky SB, Newman AB, Colbert LH, Pahor M, Rubin SM, Tylavsky FA, Visser M; Health ABC Study. Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci. 2009 Nov;64(11):1183-9. Epub 2009 Jul 21. PubMed PMID: 19622801; PubMed Central PMCID: PMC2759573.


Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009 Jul 16;460(7253):392-5. Epub 2009 Jul 8. PubMed PMID: 19587680; PubMed Central PMCID: PMC2786175.


Landi F, Russo A, Liperoti R, Danese P, Maiorana E, Pahor M, Bernabei R, Onder G. Daily pain and functional decline among old-old adults living in the community: results from the ilSIRENTE Study. J Pain Symptom Manage. 2009 Sep;38(3):350-7. Epub 2009 Apr 8. PubMed PMID: 19359134.


Working Group on Functional Outcome Measures for Clinical Trials, Bhasin S, Espeland MA, Evans WJ, Ferrucci L, Fried LP, Gill TM, Pahor M, Studenski S, Guralnik J, Nayfield S, Romashkin S, Perlstein R, Burke L, Parks M. Indications, labeling, and outcomes assessment for drugs aimed at improving functional status in older persons: a conversation between aging researchers and FDA regulators. J Gerontol A Biol Sci Med Sci. 2009 Apr;64(4):487-91. Epub 2009 Mar 6. Review. PubMed PMID: 19270182; PubMed Central PMCID: PMC2657175.


Williamson JD, Espeland M, Kritchevsky SB, Newman AB, King AC, Pahor M, Guralnik JM, Pruitt LA, Miller ME; LIFE Study Investigators. Changes in cognitive function in a randomized trial of physical activity: results of the lifestyle interventions and independence for elders pilot study. J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):688-94. Epub 2009 Feb 24. PubMed PMID: 19244157; PubMed Central PMCID: PMC2679423.


Cesari M, Kritchevsky SB, Newman AB, Simonsick EM, Harris TB, Penninx BW, Brach JS, Tylavsky FA, Satterfield S, Bauer DC, Rubin SM, Visser M, Pahor M; Health, Aging and Body Composition Study. Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study. J Am Geriatr Soc. 2009 Feb;57(2):251-9. PubMed PMID: 19207142; PubMed Central PMCID: PMC2695653.


Brinkley TE, Leng X, Miller ME, Kitzman DW, Pahor M, Berry MJ, Marsh AP, Kritchevsky SB, Nicklas BJ. Chronic inflammation is associated with low physical function in older adults across multiple comorbidities. J Gerontol A Biol Sci Med Sci. 2009 Apr;64(4):455-61. Epub 2009 Feb 4. PubMed PMID: 19196644; PubMed Central PMCID: PMC2657165.


Cesari M, Kritchevsky SB, Atkinson HH, Penninx BW, Di Bari M, Tracy RP, Pahor M. Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. Am Heart J. 2009 Feb;157(2):334.e1-8. PubMed PMID: 19185642.


Cesari M, Pahor M, Lauretani F, Zamboni V, Bandinelli S, Bernabei R, Guralnik JM, Ferrucci L. Skeletal muscle and mortality results from the InCHIANTI Study. J Gerontol A Biol Sci Med Sci. 2009 Mar;64(3):377-84. Epub 2009 Jan 30. PubMed PMID: 19181709; PubMed Central PMCID: PMC2655006.


Vestergaard S, Patel KV, Walkup MP, Pahor M, Marsh AP, Espeland MA, Studenski S, Gill TM, Church T, Guralnik JM. Stopping to rest during a 400-meter walk and incident mobility disability in older persons with functional limitations. J Am Geriatr Soc. 2009 Feb;57(2):260-5. Epub 2008 Dec 10. PubMed PMID: 19170785; PubMed Central PMCID: PMC2640434.


Beasley LE, Koster A, Newman AB, Javaid MK, Ferrucci L, Kritchevsky SB, Kuller LH, Pahor M, Schaap LA, Visser M, Rubin SM, Goodpaster BH, Harris TB; Health ABC study. Inflammation and race and gender differences in computerized tomography-measured adipose depots. Obesity (Silver Spring). 2009 May;17(5):1062-9. Epub 2009 Jan 22. PubMed PMID: 19165157; PubMed Central PMCID: PMC3268118.


Penninx BW, Nicklas BJ, Newman AB, Harris TB, Goodpaster BH, Satterfield S, de Rekeneire N, Yaffe K, Pahor M, Kritchevsky SB; Health ABC Study. Metabolic syndrome and physical decline in older persons: results from the Health, Aging And Body Composition Study. J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):96-102. Epub 2009 Jan 20. PubMed PMID: 19164274; PubMed Central PMCID: PMC2691185.


Cesari M, Onder G, Zamboni V, Manini T, Shorr RI, Russo A, Bernabei R, Pahor M, Landi F. Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study. BMC Geriatr. 2008 Dec 22;8:34. PubMed PMID: 19102751; PubMed Central PMCID: PMC2628909.


Church TS, Gill TM, Newman AB, Blair SN, Earnest CP, Pahor M. Maximal fitness testing in sedentary elderly at substantial risk of disability: LIFE-P study experience. J Aging Phys Act. 2008 Oct;16(4):408-15. PubMed PMID: 19033602; PubMed Central PMCID: PMC3056455.


Cesari M, Pahor M, Marzetti E, Zamboni V, Colloca G, Tosato M, Patel KV, Tovar JJ, Markides K. Self-assessed health status, walking speed and mortality in older Mexican-Americans. Gerontology. 2009;55(2):194-201. Epub 2008 Nov 18. PubMed PMID: 19018125; PubMed Central PMCID: PMC2790745.


Nicklas BJ, Hsu FC, Brinkley TJ, Church T, Goodpaster BH, Kritchevsky SB, Pahor M. Exercise training and plasma C-reactive protein and interleukin-6 in elderly people. J Am Geriatr Soc. 2008 Nov;56(11):2045-52. PubMed PMID: 19016938; PubMed Central PMCID: PMC2683336.


Goodpaster BH, Chomentowski P, Ward BK, Rossi A, Glynn NW, Delmonico MJ, Kritchevsky SB, Pahor M, Newman AB. Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial. J Appl Physiol. 2008 Nov;105(5):1498-503. Epub 2008 Sep 25. PubMed PMID: 18818386; PubMed Central PMCID: PMC2584841.


Landi F, Russo A, Cesari M, Pahor M, Liperoti R, Danese P, Bernabei R, Onder G. Walking one hour or more per day prevented mortality among older persons: results from ilSIRENTE study. Prev Med. 2008 Oct;47(4):422-6. Epub 2008 Jul 11. PubMed PMID: 18672001.


Mangani I, Cesari M, Russo A, Onder G, Maraldi C, Zamboni V, Marchionni N, Bernabei R, Pahor M, Landi F. Physical function, physical activity and recent falls. Results from the “Invecchiamento e LongevitĂ  nel Sirente (ilSIRENTE)” Study. Aging Clin Exp Res. 2008 Jun;20(3):234-41. PubMed PMID: 18594191.


Rejeski WJ, King AC, Katula JA, Kritchevsky S, Miller ME, Walkup MP, Glynn NW, Pahor M; LIFE Investigators. Physical activity in prefrail older adults: confidence and satisfaction related to physical function. J Gerontol B Psychol Sci Soc Sci. 2008 Jan;63(1):P19-26. PubMed PMID: 18332190.


Working Group on Functional Outcome Measures for Clinical Trials. Functional outcomes for clinical trials in frail older persons: time to be moving. J Gerontol A Biol Sci Med Sci. 2008 Feb;63(2):160-4. PubMed PMID: 18314451; PubMed Central PMCID: PMC2645663.


Landi F, Russo A, Pahor M, Capoluongo E, Liperoti R, Cesari M, Bernabei R, Onder G. Serum high-density lipoprotein cholesterol levels and mortality in frail, community-living elderly. Gerontology. 2008;54(2):71-8. Epub 2007 Nov 15. PubMed PMID: 18025809.