Pahor, Marco, M.D.

Published: March 15th, 2012

Category: Faculty, IOA Executive Board

Profile Picture


Professor and Founding Chair, Department of Aging and Geriatric Research
Director, Institute on Aging
College of Medicine, University of Florida
Gainesville, FL


2004 Mowry Road, Gainesville, Fl 32611
PO Box 100107, Gainesville, FL 32610.






Departmental Affiliation

Department of Aging and Geriatric Research
College of Medicine
Institute on Aging


Undergraduate: Baccalaureate in Biological Sciences, Lycee Chateaubriand, French School, Rome, Italy, June 1974
Graduate: Medical Doctor degree, Catholic University, Rome, Italy, November 1974 - November 1980
o Internal Medicine, University Hospital A. Gemelli, Rome, Italy, November 1977 - July 1978
o Internal Medicine, Martigny Hospital, Martigny, Switzerland, August 1-31, 1978
o Geriatrics, University Hospital A. Gemelli, Rome, Italy, September 1978 - November 1980
o Cardiology, Sahlgrenska Hospital, Gothenburg, Sweden, August 1-31, 1979
Residency: Internal Medicine and Geriatrics, University Hospital A. Gemelli, Rome, Italy, December 1980 - February 1985
Postgraduate: Specialty Thesis in Geriatrics and Gerontology, Catholic University, Rome, Italy, November 1980 - November 1984, with honors Specialty Thesis in Internal Medicine, Catholic University, Rome, Italy. November 1985 - July 1990, with honors

Geriatrics Specialty Board Italy, November 1984 Internal Medicine Specialty Board Italy, July 1990

Additional Information

Marco Pahor, MD, is the director of the University of Florida Institute on Aging, and the founding chairman of the department of aging and geriatric research in the UF College of Medicine. Pahor is an internationally recognized expert on population-based studies, clinical trials and multidisciplinary translational research in the fields of aging and disability. Dr. Pahor has an excellent publication record, having authored or co-authored more than 420 papers in leading peer-reviewed journals. He has an extensive portfolio of grants from the National Institutes of Health and other agencies, and is leader in education, serving as director of faculty mentoring programs of the Claude D. Pepper Older Americans Independence Center.

Pahor served on the Physical Exercise Task Force and the Aging Clinical Trials Advisory Panel of the National Institute on Aging. He has served as an editor for a number of academic journals, including Aging, Clinical and Experimental Research, the Journal of the American Geriatrics Society, the Journal of Gerontology: Medical Sciences and the Journal of Nutrition, Health and Aging. He has served on numerous NIH grant and program review panels.


o Assistant Professor, Department of Internal Medicine and Geriatrics, Catholic University, Rome, Italy, March 1986 - June 1996. Tenured from 1991 through 1999.
o Contract Professor of Geriatrics and Gerontology, Catholic University, College of Medicine, Rome, Italy, November 1999 - 2000
o Contract Professor, Department of Pharmacology, College of Medicine, University of Florence, Florence, Italy, November 1994 - 1999
o Associate Professor of Preventive Medicine, University of Tennessee, Memphis, TN, July 1996 – June 1999
o Professor of Preventive Medicine with tenure, Department of Preventive Medicine, University of Tennessee, Memphis, July 1999
o Professor of Internal Medicine, and Gerontology and Geriatrics with tenure, Wake Forest University School of Medicine, Winston Salem, NC, July 1999 – January 2005
o Director, Sticht Center on Aging and Rehabilitation, Wake Forest University School of Medicine, Winston Salem, NC, July 1999 – January 2005
o Deputy Associate Dean for Research, Wake Forest University School of Medicine, Winston Salem, NC, July 2002 – July 2004
o Acting Director, Geriatric Research, Education and Clinical Center (GRECC) North Florida, South Georgia Veterans Health System, Gainesville, FL, April 2006-January 2007
o Director Institute on Aging, University of Florida, Gainesville, FL, February 2005-present
o Professor with tenure and Chair department of Aging and Geriatric Research, College of Medicine, University of Florida, Gainesville, FL, February 2005-present
o Assistant Physician, Outpatient Geriatric Clinic, University Hospital A. Gemelli, Rome Italy, March 1986 - January 1991
o Chief Physician, Outpatient Geriatric Clinic, University Hospital A. Gemelli, Rome Italy, February 1991 - June 1996
o Associate Professor, Preventive Medicine, UT Medical Group, Memphis, July 1996 – July 1999
o Chief Section on Gerontology and Geriatrics, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, July 1999 – January 2005


o Italian Society of Internal Medicine for his scientific contribution in 1987
o Italian Society of Cardiology for the best study on the therapy of hypertension with angiotensin converting enzyme inhibitors in 1989.
o Italian National Academy of "Lincei" in recognition and appreciation for the studies of pharmacoepidemiology in the elderly in 1989.
o US Department of Health and Human Services, Public Health Service, National Institutes of Health, in recognition and appreciation for scientific contributions and administrative oversight during the planning and development of the Women's Health and Aging Study (WHAS), 1994.
o US Department of Justice, Immigration and Naturalization Service, Alien of Extraordinary Ability for his outstanding academic, scientific and professional achievements, October 1996
o Memphis Hypertension Preventive Medicine Coalition, for his invaluable voluntary assistance in the screening, monitoring and education of Memphis/Shelby County Residents for high Blood Pressure, 1998
o Premio Enrico Greppi award from Italy's Societa Italiana di Gerontologia e Geriatria (SIGG) for dedicating his career to the improvement of the health and quality of life of elderly people worldwide. The award is given in memory of the founder of SIGG and the International Association of Gerontology - 2008

Professional Interests

Geriatric Research, Physical Function, Disability, Epidemiology, Randomized Control Trials



Selected Peer-reviewed Publications (Selected from over 300 peer-reviewed publications)


Bann D, Hire D, Manini T, Cooper R, Botoseneanu A, McDermott MM, Pahor M, Glynn NW, Fielding R, King AC, Church T, Ambrosius WT, Gill TM. Correction: Light Intensity Physical Activity and Sedentary Behavior in Relation to Body Mass Index and Grip Strength in Older Adults: Cross-Sectional Findings from the Lifestyle Interventions and Independence for Elders (LIFE) Study. PLoS ONE 2015; 10(4):e0126063.

Botoseneanu A, Ambrosius WT, Beavers DP, de RN, Anton S, Church T, Folta SC, Goodpaster BH, King AC, Nicklas BJ, Spring B, Wang X, Gill TM. Prevalence of metabolic syndrome and its association with physical capacity, disability, and self-rated health in Lifestyle Interventions and Independence for Elders Study participants. J Am Geriatr Soc 2015; 63(2):222-232. PMCID: PMC4333053

Cauley JA, Fluharty L, Ellenberg SS, Gill TM, Ensrud KE, Barrett-Connor E, Cifelli D, Cunningham GR, Matsumoto AM, Bhasin S, Pahor M, Farrar JT, Cella D, Rosen RC, Resnick SM, Swerdloff RS, Lewis CE, Molitch ME, Crandall JP, Stephens-Shields AJ, Strorer TW, Wang C, Anton S, Basaria S, Diem S, Tabatabaie V, Dougar D, Hou X, Snyder PJ. Recruitment and Screening for the Testosterone Trials. J Gerontol A Biol Sci Med Sci 2015.

Cesari M, Vellas B, Hsu FC, Newman AB, Doss H, King AC, Manini TM, Church T, Gill TM, Miller ME, Pahor M. A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study. J Gerontol A Biol Sci Med Sci 2015; 70(2):216-222. PMCID: PMC4311184

Cunningham GR, Stephens-Shields AJ, Rosen RC, Wang C, Ellenberg SS, Matsumoto AM, Bhasin S, Molitch ME, Farrar JT, Cella D, Barrett-Connor E, Cauley JA, Cifelli D, Crandall JP, Ensrud KE, Fluharty L, Gill TM, Lewis CE, Pahor M, Resnick SM, Storer TW, Swerdloff RS, Anton S, Basaria S, Diem S, Tabatabaie V, Hou X, Snyder PJ. Association of sex hormones with sexual function, vitality, and physical function of symptomatic older men with low testosterone levels at baseline in the testosterone trials. J Clin Endocrinol Metab 2015; 100(3):1146-1155. PMCID: PMC4333035

Fitzgerald JD, Johnson L, Hire DG, Ambrosius WT, Anton SD, Dodson JA, Marsh AP, McDermott MM, Nocera JR, Tudor-Locke C, White DK, Yank V, Pahor M, Manini TM, Buford TW. Association of objectively measured physical activity with cardiovascular risk in mobility-limited older adults. J Am Heart Assoc 2015; 4(2). PMCID: PMC4345863

Beavers KM, Hsu FC, Serra MC, Yank V, Pahor M, Nicklas BJ. The Effects of a Long-term Physical Activity Intervention on Serum Uric Acid in Older Adults at Risk for Physical Disability. J Aging Phys Act 2014; 22(1):25-33. PMCID: PMID: 24363000

Buford TW, Hsu FC, Brinkley TE, Carter CS, Church TS, Dodson JA, Goodpaster BH, McGrae MM, Nicklas BJ, Yank V, Johnson JA, Pahor M. Genetic Influence on Exercise-Induced Changes in Physical Function among Mobility-Limited Older Adults. Physiol Genomics 2014. PMCID: PMID: 24423970

Liu CK, Leng X, Hsu FC, Kritchevsky SB, Ding J, Earnest CP, Ferrucci L, Goodpaster BH, Guralnik JM, Lenchik L, Pahor M, Fielding RA. The Impact of Sarcopenia on a Physical Activity Intervention: The Lifestyle Interventions and Independence for Elders Pilot Study (LIFE-P). J Nutr Health Aging 2014; 18(1):59-64. PMCID: PMID: 24402391

Marzetti E, Landi F, Marini F, Cesari M, Buford TW, Manini TM, Onder G, Pahor M, Bernabei R, Leeuwenburgh C, Calvani R. Patterns of circulating inflammatory biomarkers in older persons with varying levels of physical performance: a partial least squares-discriminant analysis approach. Front Med (Lausanne) 2014; 1:27. PMCID: PMC4292189

O’Hartaigh B, Pahor M, Buford TW, Dodson JA, Forman DE, Gill TM. Physical activity and resting pulse rate in older adults: Findings from a randomized controlled trial. Am Heart J 2014; 168(4):597-604. PMCID: PMC4180058

Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD. Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial. JAMA 2014; 311(23):2387-2396. PMCID: 24866862

Sink KM, Espeland MA, Rushing J, Castro CM, Church TS, Cohen R, Gill TM, Henkin L, Jennings JM, Kerwin DR, Manini TM, Myers V, Pahor M, Reid KF, Woolard N, Rapp SR, Williamson JD. The LIFE Cognition Study: design and baseline characteristics. Clin Interv Aging 2014; 9:1425-1436. PMCID: PMC4154884

Snyder PJ, Ellenberg SS, Cunningham GR, Matsumoto AM, Bhasin S, Barrett-Connor E, Gill TM, Farrar JT, Cella D, Rosen RC, Resnick SM, Swerdloff RS, Cauley JA, Cifelli D, Fluharty L, Pahor M, Ensrud KE, Lewis CE, Molitch ME, Crandall JP, Wang C, Budoff MJ, Wenger NK, Mohler ER, III, Bild DE, Cook NL, Keaveny TM, Kopperdahl DL, Lee D, Schwartz AV, Storer TW, Ershler WB, Roy CN, Raffel LJ, Romashkan S, Hadley E. The Testosterone Trials: Seven coordinated trials of testosterone treatment in elderly men. Clin Trials 2014; 11(3):362-375.

Vaz Fragoso CA, Beavers DP, Hankinson JL, Flynn G, Berra K, Kritchevsky SB, Liu CK, McDermott MM, Manini TM, Rejeski WJ, Gill TM. Respiratory impairment and dyspnea and their associations with physical inactivity and mobility in sedentary community-dwelling older persons. J Am Geriatr Soc 2014; 62(4):622-628. PMCID: PMC3989438

Vaz Fragoso CA, Miller ME, Fielding RA, King AC, Kritchevsky SB, McDermott MM, Myers V, Newman AB, Pahor M, Gill TM. Sleep-Wake Disturbances in Sedentary Community-Dwelling Elderly Adults with Functional Limitations. J Am Geriatr Soc 2014.

Vaz Fragoso CA, Hsu FC, Brinkley T, Church T, Liu CK, Manini T, Newman AB, Stafford RS, McDermott MM, Gill TM. Combined reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease in sedentary elders with functional limitations. J Am Med Dir Assoc 2014; 15(9):665-670. PMCID: PMC4145029

Study design of ASPirin in Reducing Events in the Elderly (ASPREE): a randomized, controlled trial. Contemp Clin Trials 2013; 36(2):555-564.

Buford TW, Macneil RG, Clough LG, Dirain M, Sandesara B, Pahor M, Manini TM, Leeuwenburgh C. Active muscle regeneration following eccentric contraction-induced injury is similar between healthy young and older adults. J Appl Physiol 2013; e publ. PMCID: PMID: 23493365

Endeshaw Y, Rice TB, Schwartz AV, Stone KL, Manini TM, Satterfield S, Cummings S, Harris T, Pahor M. Snoring, daytime sleepiness, and incident cardiovascular disease in the health, aging, and body composition study. Sleep 2013; 36(11):1737-1745. PMCID: PMC3792392

Ferry M, Coley N, Andrieu S, Bonhomme C, Caubere JP, Cesari M, Gautry J, Garcia S, I, Hugonot L, Mansuy L, Pahor M, Pariente J, Ritz P, Salva A, Sijben J, Wieggers R, Ythier-Moury P, Zaim M, Zetlaoui J, Vellas B. How to design nutritional intervention trials to slow cognitive decline in apparently healthy populations and apply for efficacy claims: a statement from the International Academy on Nutrition and Aging Task Force. J Nutr Health Aging 2013; 17(7):619-623.

Groffen DA, Koster A, Bosma H, van den Akker M, Kempen GI, van Eijk JT, van Gool CH, Penninx BW, Harris TB, Rubin SM, Pahor M, Schulz R, Simonsick EM, Perry SE, Ayonayon HN, Kritchevsky SB. Unhealthy Lifestyles Do Not Mediate the Relationship Between Socioeconomic Status and Incident Depressive Symptoms: The Health ABC study. Am J Geriatr Psychiatry 2013. PMCID: PMC3402597

Landi F, Marzetti E, Liperoti R, Pahor M, Russo A, Martone AM, Colloca G, Capoluongo E, Bernabei R. Nonsteroidal anti-inflammatory drug (NSAID) use and sarcopenia in older people: results from the ilSIRENTE study. J Am Med Dir Assoc 2013; 14(8):626-13.

Manini TM, Buford TW, Lott DJ, Vandenborne K, Daniels MJ, Knaggs JD, Patel H, Pahor M, Perri MG, Anton SD. Effect of Dietary Restriction and Exercise on Lower Extremity Tissue Compartments in Obese, Older Women: A Pilot Study. J Gerontol A Biol Sci Med Sci 2013.

Marsh AP, Lovato LC, Glynn NW, Kennedy K, Castro C, Domanchuk K, McDavitt E, Rodate R, Marsiske M, McGloin J, Groessl EJ, Pahor M, Guralnik JM. Lifestyle Interventions and Independence for Elders Study: Recruitment and Baseline Characteristics. J Gerontol A Biol Sci Med Sci 2013; 68(12):1549-1558. PMCID: PMC3814232

McDermott MM, Applegate WB, Bonds DE, Buford TW, Church T, Espeland MA, Gill TM, Guralnik JM, Haskell W, Lovato LC, Pahor M, Pepine CJ, Reid KF, Newman A. Ankle brachial index values, leg symptoms, and functional performance among community-dwelling older men and women in the lifestyle interventions and independence for elders study. J Am Heart Assoc 2013; 2(6):e000257. PMCID: PMC3886743

Milaneschi Y, Cesari M, Simonsick EM, Vogelzangs N, Kanaya AM, Yaffe K, Patrignani P, Metti A, Kritchevsky SB, Pahor M, Ferrucci L, Penninx BW. Lipid peroxidation and depressed mood in community-dwelling older men and women. PLoS ONE 2013; 8(6):e65406. PMCID: PMC3679197

Rejeski WJ, Axtell R, Fielding R, Katula J, King AC, Manini TM, Marsh AP, Pahor M, Rego A, Tudor-Locke C, Newman M, Walkup MP, Miller ME. Promoting physical activity for elders with compromised function: the lifestyle Interventions and Independence for elders (LIFE) study physical activity intervention. Clin Interv Aging 2013; 8:1119-1131. PMCID: PMC3775623

Vellas B, Pahor M, Manini T, Rooks D, Guralnik JM, Morley J, Studenski S, Evans W, Asbrand C, Fariello R, Pereira S, Rolland Y, Abellan Van KG, Cesari M, Chumlea WC, Fielding R. Designing pharmaceutical trials for sarcopenia in frail older adults: EU/US Task Force recommendations. J Nutr Health Aging 2013; 17(7):612-618.

Woods AJ, Cohen RA, Pahor M. Cognitive frailty: frontiers and challenges. J Nutr Health Aging 2013; 17(9):741-743.

Buford TW, Manini TM, Hsu FC, Cesari M, Anton SD, Nayfield S, Stafford RS, Church TS, Pahor M, Carter CS. Angiotensin-converting enzyme inhibitor use by older adults is associated with greater functional responses to exercise. J Am Geriatr Soc. 2012 Jul;60(7):1244-52. doi: 10.1111/j.1532-5415.2012.04045.x. Epub 2012 Jun 21. PubMed PMID: 22726232.


Joseph AM, Adhihetty PJ, Buford TW, Wohlgemuth SE, Lees HA, Nguyen LM, Aranda JM, Sandesara BD, Pahor M, Manini TM, Marzetti E, Leeuwenburgh C. The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals. Aging Cell. 2012 Jun 8. doi: 10.1111/j.1474-9726.2012.00844.x. [Epub ahead of print] PubMed PMID: 22681576.


Buford TW, Pahor M. Making preventive medicine more personalized: Implications for exercise-related research. Prev Med. 2012 Jul;55(1):34-6. Epub 2012 May 14. PubMed PMID: 22588227.


Groffen DA, Koster A, Bosma H, van den Akker M, Kempen GI, van Eijk JT, van Gool CH, Penninx BW, Harris TB, Rubin SM, Pahor M, Schulz R, Simonsick EM, Perry SE, Ayonayon HN, Kritchevsky SB; for the Health ABC study. Unhealthy Lifestyles Do Not Mediate the Relationship Between Socioeconomic Status and Incident Depressive Symptoms: The Health ABC study. Am J Geriatr Psychiatry. 2012 Apr 16. [Epub ahead of print] PubMed PMID: 22510729.


Brinkley TE, Hsu FC, Beavers KM, Church TS, Goodpaster BH, Stafford RS, Pahor M, Kritchevsky SB, Nicklas BJ. Total and Abdominal Adiposity Are Associated With Inflammation in Older Adults Using a Factor Analysis Approach. J Gerontol A Biol Sci Med Sci. 2012 Mar 26. [Epub ahead of print] PubMed PMID: 22451470.


Marzetti E, Lees HA, Manini TM, Buford TW, Aranda JM Jr, Calvani R, Capuani G, Marsiske M, Lott DJ, Vandenborne K, Bernabei R, Pahor M, Leeuwenburgh C, Wohlgemuth SE. Skeletal muscle apoptotic signaling predicts thigh muscle volume and gait speed in community-dwelling older persons: an exploratory study. PLoS One. 2012;7(2):e32829. Epub 2012 Feb 28. PubMed PMID: 22389725; PubMed Central PMCID: PMC3289676.


Cesari M, Kritchevsky SB, Nicklas B, Kanaya AM, Patrignani P, Tacconelli S, Tranah GJ, Tognoni G, Harris TB, Incalzi RA, Newman AB, Pahor M; Health ABC study. Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study. J Gerontol A Biol Sci Med Sci. 2012 Jun;67(6):671-6. Epub 2012 Mar 1. PubMed PMID: 22389462; PubMed Central PMCID: PMC3348494.


Sourdet S, Van Kan GA, Soto ME, Houles M, Cantet C, Nourhashemi F, Vellas B, Pahor M, Rolland Y. Prognosis of an abnormal one-leg balance in community-dwelling patients with Alzheimer’s disease: a 2-year prospective study in 686 patients of the REAL.FR study. J Am Med Dir Assoc. 2012 May;13(4):407.e1-6. Epub 2012 Jan 9. PubMed PMID: 22227074.


Wang X, Hsu FC, Isom S, Walkup MP, Kritchevsky SB, Goodpaster BH, Church TS, Pahor M, Stafford RS, Nicklas BJ. Effects of a 12-month physical activity intervention on prevalence of metabolic syndrome in elderly men and women. J Gerontol A Biol Sci Med Sci. 2012 Apr;67(4):417-24. Epub 2011 Oct 24. PubMed PMID: 22024949; PubMed Central PMCID: PMC3309873.


Buford TW, Lott DJ, Marzetti E, Wohlgemuth SE, Vandenborne K, Pahor M, Leeuwenburgh C, Manini TM. Age-related differences in lower extremity tissue compartments and associations with physical function in older adults. Exp Gerontol. 2012 Jan;47(1):38-44. Epub 2011 Oct 12. PubMed PMID: 22015325; PubMed Central PMCID: PMC3245356.


Nocera J, Buford TW, Manini TM, Naugle K, Leeuwenburgh C, Pahor M, Perri MG, Anton SD. The impact of behavioral intervention on obesity mediated declines in mobility function: implications for longevity. J Aging Res. 2011;2011:392510. Epub 2011 Oct 16. PubMed PMID: 22013527; PubMed Central PMCID: PMC3195552.


Marsh AP, Rejeski WJ, Espeland MA, Miller ME, Church TS, Fielding RA, Gill TM, Guralnik JM, Newman AB, Pahor M; LIFE Study Investigators. Muscle strength and BMI as predictors of major mobility disability in the Lifestyle Interventions and Independence for Elders pilot (LIFE-P). J Gerontol A Biol Sci Med Sci. 2011 Dec;66(12):1376-83. Epub 2011 Oct 5. PubMed PMID: 21975090; PubMed Central PMCID: PMC3210962.


Giovannini S, Onder G, Liperoti R, Russo A, Carter C, Capoluongo E, Pahor M, Bernabei R, Landi F. Interleukin-6, C-reactive protein, and tumor necrosis factor-alpha as predictors of mortality in frail, community-living elderly individuals. J Am Geriatr Soc. 2011 Sep;59(9):1679-85. doi: 10.1111/j.1532-5415.2011.03570.x. Epub 2011 Aug 24. PubMed PMID: 21883115.


Fielding RA, Rejeski WJ, Blair S, Church T, Espeland MA, Gill TM, Guralnik JM, Hsu FC, Katula J, King AC, Kritchevsky SB, McDermott MM, Miller ME, Nayfield S, Newman AB, Williamson JD, Bonds D, Romashkan S, Hadley E, Pahor M; LIFE Research Group. The Lifestyle Interventions and Independence for Elders Study: design and methods. J Gerontol A Biol Sci Med Sci. 2011 Nov;66(11):1226-37. Epub 2011 Aug 8. PubMed PMID: 21825283; PubMed Central PMCID: PMC3193523.


Anton SD, Manini TM, Milsom VA, Dubyak P, Cesari M, Cheng J, Daniels MJ, Marsiske M, Pahor M, Leeuwenburgh C, Perri MG. Effects of a weight loss plus exercise program on physical function in overweight, older women: a randomized controlled trial. Clin Interv Aging. 2011;6:141-9. doi: 10.2147/CIA.S17001. Epub 2011 Jun 15. PubMed PMID: 21753869; PubMed Central PMCID: PMC3131984.


Wohlgemuth SE, Lees HA, Marzetti E, Manini TM, Aranda JM, Daniels MJ, Pahor M, Perri MG, Leeuwenburgh C, Anton SD. An exploratory analysis of the effects of a weight loss plus exercise program on cellular quality control mechanisms in older overweight women. Rejuvenation Res. 2011 Jun;14(3):315-24. Epub 2011 Jun 1. PubMed PMID: 21631380; PubMed Central PMCID: PMC3136739.


Chumlea WC, Cesari M, Evans WJ, Ferrucci L, Fielding RA, Pahor M, Studenski S, Vellas B; International Working Group on Sarcopenia Task Force Members. Sarcopenia: designing phase IIB trials. J Nutr Health Aging. 2011 Jun;15(6):450-5. PubMed PMID: 21623466; PubMed Central PMCID: PMC3367322.


Pahor M. Consideration of insurance reimbursement for physical activity and exercise programs for patients with diabetes. JAMA. 2011 May 4;305(17):1808-9. PubMed PMID: 21540427.


Cesari M, Incalzi RA, Zamboni V, Pahor M. Vitamin D hormone: a multitude of actions potentially influencing the physical function decline in older persons. Geriatr Gerontol Int. 2011 Apr;11(2):133-42. doi: 10.1111/j.1447-0594.2010.00668.x. Epub 2010 Dec 6. Review. PubMed PMID: 21134097.


Cesari M, Pahor M, Incalzi RA. Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions. Cardiovasc Ther. 2010 Oct;28(5):e72-91. doi: 10.1111/j.1755-5922.2010.00171.x. Epub 2010 Jul 7. Review. PubMed PMID: 20626406; PubMed Central PMCID: PMC2958211.


Landi F, Russo A, Liperoti R, Tosato M, Barillaro C, Pahor M, Bernabei R, Onder G. Anorexia, physical function, and incident disability among the frail elderly population: results from the ilSIRENTE study. J Am Med Dir Assoc. 2010 May;11(4):268-74. Epub 2010 Apr 3. PubMed PMID: 20439047.


Buford TW, Anton SD, Judge AR, Marzetti E, Wohlgemuth SE, Carter CS, Leeuwenburgh C, Pahor M, Manini TM. Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy. Ageing Res Rev. 2010 Oct;9(4):369-83. Epub 2010 May 14. Review. PubMed PMID: 20438881.


Beavers KM, Hsu FC, Isom S, Kritchevsky SB, Church T, Goodpaster B, Pahor M, Nicklas BJ. Long-term physical activity and inflammatory biomarkers in older adults. Med Sci Sports Exerc. 2010 Dec;42(12):2189-96. PubMed PMID: 20421832; PubMed Central PMCID: PMC2964389.


Rosano C, Venkatraman VK, Guralnik J, Newman AB, Glynn NW, Launer L, Taylor CA, Williamson J, Studenski S, Pahor M, Aizenstein H. Psychomotor speed and functional brain MRI 2 years after completing a physical activity treatment. J Gerontol A Biol Sci Med Sci. 2010 Jun;65(6):639-47. Epub 2010 Mar 26. PubMed PMID: 20348185; PubMed Central PMCID: PMC2869531.


Koster A, van Gool CH, Kempen GI, Penninx BW, Lee JS, Rubin SM, Tylavsky FA, Yaffe K, Newman AB, Harris TB, Pahor M, Ayonayon HN, van Eijk JT, Kritchevsky SB; Health ABC Study. Late-life depressed mood and weight change contribute to the risk of each other. Am J Geriatr Psychiatry. 2010 Mar;18(3):236-44. PubMed PMID: 20224519; PubMed Central PMCID: PMC2838199.


Marzetti E, Privitera G, Simili V, Wohlgemuth SE, Aulisa L, Pahor M, Leeuwenburgh C. Multiple pathways to the same end: mechanisms of myonuclear apoptosis in sarcopenia of aging. ScientificWorldJournal. 2010 Feb 19;10:340-9. Review. PubMed PMID: 20191247.


Cesari M, Pedone C, Incalzi RA, Pahor M. ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. J Am Med Dir Assoc. 2010 Jan;11(1):26-32. Epub 2009 Nov 25. PubMed PMID: 20129212; PubMed Central PMCID: PMC2818218.


Landi F, Russo A, Liperoti R, Pahor M, Tosato M, Capoluongo E, Bernabei R, Onder G. Midarm muscle circumference, physical performance and mortality: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study). Clin Nutr. 2010 Aug;29(4):441-7. Epub 2010 Feb 8. PubMed PMID: 20116909.


Groessl EJ, Kaplan RM, Blair SN, Rejeski WJ, Katula JA, King AC, Fielding RA, Glynn NW, Pahor M. A cost analysis of a physical activity intervention for older adults. J Phys Act Health. 2009 Nov;6(6):767-74. PubMed PMID: 20101920; PubMed Central PMCID: PMC3091594.


Williamson J, Pahor M. Evidence regarding the benefits of physical exercise. Arch Intern Med. 2010 Jan 25;170(2):124-5. PubMed PMID: 20101006.


Giovannini S, Onder G, Leeuwenburgh C, Carter C, Marzetti E, Russo A, Capoluongo E, Pahor M, Bernabei R, Landi F. Myeloperoxidase levels and mortality in frail community-living elderly individuals. J Gerontol A Biol Sci Med Sci. 2010 Apr;65(4):369-76. Epub 2010 Jan 11. PubMed PMID: 20064836.


Landi F, Liperoti R, Russo A, Capoluongo E, Barillaro C, Pahor M, Bernabei R, Onder G. Disability, more than multimorbidity, was predictive of mortality among older persons aged 80 years and older. J Clin Epidemiol. 2010 Jul;63(7):752-9. Epub 2010 Jan 8. PubMed PMID: 20056387.


Venkatraman VK, Aizenstein H, Guralnik J, Newman AB, Glynn NW, Taylor C, Studenski S, Launer L, Pahor M, Williamson J, Rosano C. Executive control function, brain activation and white matter hyperintensities in older adults. Neuroimage. 2010 Feb 15;49(4):3436-42. Epub 2009 Nov 14. Erratum in: Neuroimage. 2010 May 1;50(4):1711. PubMed PMID: 19922803; PubMed Central PMCID: PMC2818521.


Cesari M, Marzetti E, Laudisio A, Antonica L, Pahor M, Bernabei R, Zuccalà G. Interaction of HDL cholesterol concentrations on the relationship between physical function and inflammation in community-dwelling older persons. Age Ageing. 2010 Jan;39(1):74-80. Epub 2009 Nov 5. PubMed PMID: 19892744; PubMed Central PMCID: PMC2800252.


Manini TM, Newman AB, Fielding R, Blair SN, Perri MG, Anton SD, Goodpaster BC, Katula JA, Rejeski WJ, Kritchevsky SB, Hsu FC, Pahor M, King AC; LIFE Research Group. Effects of exercise on mobility in obese and nonobese older adults. Obesity (Silver Spring). 2010 Jun;18(6):1168-75. Epub 2009 Oct 15. Erratum in: Obesity (Silver Spring).2011 May;19(5):1106. King, Abby C [added]. PubMed PMID: 19834467; PubMed Central PMCID: PMC3114403.


Maraldi C, Harris TB, Newman AB, Kritchevsky SB, Pahor M, Koster A, Satterfield S, Ayonayon HN, Fellin R, Volpato S; Health ABC study. Moderate alcohol intake and risk of functional decline: the Health, Aging, and Body Composition study. J Am Geriatr Soc. 2009 Oct;57(10):1767-75. Epub 2009 Sep 8. PubMed PMID: 19737328; PubMed Central PMCID: PMC3149890.


Schaap LA, Pluijm SM, Deeg DJ, Harris TB, Kritchevsky SB, Newman AB, Colbert LH, Pahor M, Rubin SM, Tylavsky FA, Visser M; Health ABC Study. Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci. 2009 Nov;64(11):1183-9. Epub 2009 Jul 21. PubMed PMID: 19622801; PubMed Central PMCID: PMC2759573.


Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009 Jul 16;460(7253):392-5. Epub 2009 Jul 8. PubMed PMID: 19587680; PubMed Central PMCID: PMC2786175.


Landi F, Russo A, Liperoti R, Danese P, Maiorana E, Pahor M, Bernabei R, Onder G. Daily pain and functional decline among old-old adults living in the community: results from the ilSIRENTE Study. J Pain Symptom Manage. 2009 Sep;38(3):350-7. Epub 2009 Apr 8. PubMed PMID: 19359134.


Working Group on Functional Outcome Measures for Clinical Trials, Bhasin S, Espeland MA, Evans WJ, Ferrucci L, Fried LP, Gill TM, Pahor M, Studenski S, Guralnik J, Nayfield S, Romashkin S, Perlstein R, Burke L, Parks M. Indications, labeling, and outcomes assessment for drugs aimed at improving functional status in older persons: a conversation between aging researchers and FDA regulators. J Gerontol A Biol Sci Med Sci. 2009 Apr;64(4):487-91. Epub 2009 Mar 6. Review. PubMed PMID: 19270182; PubMed Central PMCID: PMC2657175.


Williamson JD, Espeland M, Kritchevsky SB, Newman AB, King AC, Pahor M, Guralnik JM, Pruitt LA, Miller ME; LIFE Study Investigators. Changes in cognitive function in a randomized trial of physical activity: results of the lifestyle interventions and independence for elders pilot study. J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):688-94. Epub 2009 Feb 24. PubMed PMID: 19244157; PubMed Central PMCID: PMC2679423.


Cesari M, Kritchevsky SB, Newman AB, Simonsick EM, Harris TB, Penninx BW, Brach JS, Tylavsky FA, Satterfield S, Bauer DC, Rubin SM, Visser M, Pahor M; Health, Aging and Body Composition Study. Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study. J Am Geriatr Soc. 2009 Feb;57(2):251-9. PubMed PMID: 19207142; PubMed Central PMCID: PMC2695653.


Brinkley TE, Leng X, Miller ME, Kitzman DW, Pahor M, Berry MJ, Marsh AP, Kritchevsky SB, Nicklas BJ. Chronic inflammation is associated with low physical function in older adults across multiple comorbidities. J Gerontol A Biol Sci Med Sci. 2009 Apr;64(4):455-61. Epub 2009 Feb 4. PubMed PMID: 19196644; PubMed Central PMCID: PMC2657165.


Cesari M, Kritchevsky SB, Atkinson HH, Penninx BW, Di Bari M, Tracy RP, Pahor M. Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. Am Heart J. 2009 Feb;157(2):334.e1-8. PubMed PMID: 19185642.


Cesari M, Pahor M, Lauretani F, Zamboni V, Bandinelli S, Bernabei R, Guralnik JM, Ferrucci L. Skeletal muscle and mortality results from the InCHIANTI Study. J Gerontol A Biol Sci Med Sci. 2009 Mar;64(3):377-84. Epub 2009 Jan 30. PubMed PMID: 19181709; PubMed Central PMCID: PMC2655006.


Vestergaard S, Patel KV, Walkup MP, Pahor M, Marsh AP, Espeland MA, Studenski S, Gill TM, Church T, Guralnik JM. Stopping to rest during a 400-meter walk and incident mobility disability in older persons with functional limitations. J Am Geriatr Soc. 2009 Feb;57(2):260-5. Epub 2008 Dec 10. PubMed PMID: 19170785; PubMed Central PMCID: PMC2640434.


Beasley LE, Koster A, Newman AB, Javaid MK, Ferrucci L, Kritchevsky SB, Kuller LH, Pahor M, Schaap LA, Visser M, Rubin SM, Goodpaster BH, Harris TB; Health ABC study. Inflammation and race and gender differences in computerized tomography-measured adipose depots. Obesity (Silver Spring). 2009 May;17(5):1062-9. Epub 2009 Jan 22. PubMed PMID: 19165157; PubMed Central PMCID: PMC3268118.


Penninx BW, Nicklas BJ, Newman AB, Harris TB, Goodpaster BH, Satterfield S, de Rekeneire N, Yaffe K, Pahor M, Kritchevsky SB; Health ABC Study. Metabolic syndrome and physical decline in older persons: results from the Health, Aging And Body Composition Study. J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):96-102. Epub 2009 Jan 20. PubMed PMID: 19164274; PubMed Central PMCID: PMC2691185.


Cesari M, Onder G, Zamboni V, Manini T, Shorr RI, Russo A, Bernabei R, Pahor M, Landi F. Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study. BMC Geriatr. 2008 Dec 22;8:34. PubMed PMID: 19102751; PubMed Central PMCID: PMC2628909.


Church TS, Gill TM, Newman AB, Blair SN, Earnest CP, Pahor M. Maximal fitness testing in sedentary elderly at substantial risk of disability: LIFE-P study experience. J Aging Phys Act. 2008 Oct;16(4):408-15. PubMed PMID: 19033602; PubMed Central PMCID: PMC3056455.


Cesari M, Pahor M, Marzetti E, Zamboni V, Colloca G, Tosato M, Patel KV, Tovar JJ, Markides K. Self-assessed health status, walking speed and mortality in older Mexican-Americans. Gerontology. 2009;55(2):194-201. Epub 2008 Nov 18. PubMed PMID: 19018125; PubMed Central PMCID: PMC2790745.


Nicklas BJ, Hsu FC, Brinkley TJ, Church T, Goodpaster BH, Kritchevsky SB, Pahor M. Exercise training and plasma C-reactive protein and interleukin-6 in elderly people. J Am Geriatr Soc. 2008 Nov;56(11):2045-52. PubMed PMID: 19016938; PubMed Central PMCID: PMC2683336.


Goodpaster BH, Chomentowski P, Ward BK, Rossi A, Glynn NW, Delmonico MJ, Kritchevsky SB, Pahor M, Newman AB. Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial. J Appl Physiol. 2008 Nov;105(5):1498-503. Epub 2008 Sep 25. PubMed PMID: 18818386; PubMed Central PMCID: PMC2584841.


Landi F, Russo A, Cesari M, Pahor M, Liperoti R, Danese P, Bernabei R, Onder G. Walking one hour or more per day prevented mortality among older persons: results from ilSIRENTE study. Prev Med. 2008 Oct;47(4):422-6. Epub 2008 Jul 11. PubMed PMID: 18672001.


Mangani I, Cesari M, Russo A, Onder G, Maraldi C, Zamboni V, Marchionni N, Bernabei R, Pahor M, Landi F. Physical function, physical activity and recent falls. Results from the “Invecchiamento e Longevità nel Sirente (ilSIRENTE)” Study. Aging Clin Exp Res. 2008 Jun;20(3):234-41. PubMed PMID: 18594191.


Rejeski WJ, King AC, Katula JA, Kritchevsky S, Miller ME, Walkup MP, Glynn NW, Pahor M; LIFE Investigators. Physical activity in prefrail older adults: confidence and satisfaction related to physical function. J Gerontol B Psychol Sci Soc Sci. 2008 Jan;63(1):P19-26. PubMed PMID: 18332190.


Working Group on Functional Outcome Measures for Clinical Trials. Functional outcomes for clinical trials in frail older persons: time to be moving. J Gerontol A Biol Sci Med Sci. 2008 Feb;63(2):160-4. PubMed PMID: 18314451; PubMed Central PMCID: PMC2645663.


Landi F, Russo A, Pahor M, Capoluongo E, Liperoti R, Cesari M, Bernabei R, Onder G. Serum high-density lipoprotein cholesterol levels and mortality in frail, community-living elderly. Gerontology. 2008;54(2):71-8. Epub 2007 Nov 15. PubMed PMID: 18025809.