A native of Wintersville, Ohio, Dr. Manini attended Ohio University in Athens, OH where he graduated with honors in Biology, Exercise Science, and Biochemistry. He received his M.S. and Ph.D. as well as a Certificate of Advanced Studies in Gerontology from Syracuse University.   He completed a fellowship at the Laboratory of Epidemiology, Demography and Biometry at the National Institute on Aging at the National Institutes of Health in Bethesda, MD.  He is now a Tenured Associate Professor at the University of Florida (UF) in the Department of Aging and Geriatric Research.  He was also recently elected the prestigious honor of being standing member on NIH’s Center for Scientific Review as part of the Neurological, Aging and Musculoskeletal Epidemiology (NAME) Study Section.   He is also the Leader of the Data Science and Applied Technology Core in the UF Claude D. Pepper Older American’s Independence Center.  The Core is designed to maintain pace in a world that is becoming a connected system of computing and sensing components for mobility tracking in older adults.  His current areas of research include: 1) developing and conducting randomized interventions to combat losses in physical performance seen with aging, 2) understanding the degree to which aging modifies the metabolic cost of performing daily activities, 3) identifying the role that mitochondria have in explaining cardiovascular responsiveness to chronic physical activity and 4) developing wearable technology (e.g. smart watch) for scalable ascertainment of real-time, free-living activity and community mobility in older adults.  He receives support from the National Institute on Aging, American Heart Association, The National Heart, Lung and Blood Institute, and National Cancer Institute for his work.