Clark, David, Sc.D.
Research Associate Professor
Malcom Randall VA Medical Center (151A)
Brain Rehabilitation Research Center
1601 SW Archer Rd
Gainesville, FL 32608
Departmental AffiliationDepartment of Aging and Geriatric Research, Clinical Research Division.
B.S. in Exercise Physiology, 2001, University of Massachusetts-Lowell
Sc.D. in Rehabilitation Sciences, 2007, Boston University
Dr. David Clark holds a dual appointment as 1) Research Health Scientist with the Brain Rehabilitation Research Center (BRRC) at the Malcom Randall VA Medical Center Assistant Professor, and 2) Assistant Professor with the Department of Aging and Geriatric Research at the University of Florida (UF). He serves as a co-leader of the BRRC’s Locomotor Research Initiative. He also holds a graduate faculty appointment to mentor doctoral students in the Rehabilitation Sciences PhD program in the UF College of Public Health and Health Professions. Dr. Clark’s research and training span the domains of motor control, neuro-rehabilitation, biomechanics, and exercise physiology. His primary area of interest is optimizing mobility function in people with neurological impairments, including elderly adults and individuals who have experienced a stroke or spinal cord injury. His research seeks to develop novel interventions to enhance the neural control of walking, as well as develop novel assessments to improve measurement of neurological impairment/recovery. Dr. Clark’s research is primarily funded by the National Institutes of Health and US Department of Veterans Affairs.
Department of Aging and Geriatric Research
Clinical Research Division
College of Medicine, UF
Malcom Randall VA Medical Center, Brain Rehabilitation Research Center, Research Health Scientist and Co-Leader of the Locomotor Research Initiative.
For additional information please visit Dr. Clark’s Scholar page:
Vistamehr A, Balasubramanian CK, Clark DJ, Neptune RR, and Fox EJ. Dynamic balance during walking adaptability tasks in individuals post-stroke. J Biomech, in press, 2018.
Chatterjee SA, Daly JJ, Porges EC, Fox EJ, Rose DK, McGuirk TE, Otzel DM, Butera KA, and Clark DJ. Mobility function and recovery after stroke: preliminary insights from sympathetic nervous system activity. J Neurol Phys Ther, in press, 2018.
Hawkins KA, Fox EJ, Daly JJ, Rose DK, Christou EA, McGuirk TE, Otzel DM, Butera KA, Chatterjee SA, Clark DJ. Prefrontal over-activation during walking in people with mobility deficits: interpretation and functional implications. Hum Mov Sci, 59:46-55, 2018.
Clark DJ, Chatterjee SA, McGuirk TE, Porges EC, Fox EJ, and Balasubramanian CK. Sympathetic nervous system activity measured by skin conductance quantifies the challenge of walking adaptability tasks after stroke. Gait and Posture, 60:148-153, 2018. PMC5911926
Rose DK, DeMark L, Fox EJ, Clark DJ, and Wdyluka P. A Backward Walking Training Program to Improve Balance and Mobility in Acute Stroke: A Pilot Randomized Controlled Trial. Journal of Neurologic Physical Therapy, 42(1):12-21, 2018.
Lodha N, Chen YT, McGuirk T, Fox EJ, Kautz SA, Christou EA, and Clark DJ. EMG synchrony to assess impaired corticomotor control of locomotion after stroke. J Electromyogr Kinesiol, 37:35-40, 2017.
Hawkins KA, Clark DJ, Balasubramanian CK, and Fox EJ. Walking on uneven terrain in healthy adults and the implications for people after stroke. NeuroRehabilitation, 41(4):765-774, 2017.
Clark DJ, Neptune RR, Behrman AL and Kautz SA. Locomotor adaptability task promotes intense and task-appropriate output from the paretic leg during walking. APMR, 97(3):493-6, 2016. PMC4769939
Anton SA, Woods AJ, Ashizawa T, Barb D, Buford TW, Carter CS, Clark DJ et al. Successful Aging: Advancing the Science of Physical Independence in Older Adults. Ageing Res Rev, 24 (Pt B): 304-27, 2015. PMC4661112
Sorond FA, Cruz-Almeida Y, Clark DJ, Viswanathan A, Scherzer CR, Csiszar A, Laurienti PJ, Hausdorff J, Chen WG, Ferrucci L, Rosano C; Studenski SA, Black SE, Lipsitz LA. Aging, the Central Nervous System, and Mobility in Older Adults: Neural Mechanisms of Mobility Impairments. J Gerontol A Biol Sci Med Sci, 70(12):1526-32, 2015. PMC4643615
Clark DJ. Automaticity of walking: functional significance, mechanisms, measurement and rehabilitation strategies. Front Hum Neurosci, 246(9): 1-13, 2015.
Balasubramanian CK, Clark DJ and Gouelle A. Validity of the gait variability index in older adults: effect of aging and mobility impairments. Gait and Posture, 41: 941-946, 2015.
Reid KF, Martin KI, Doros G, Clark DJ, Hau C, Patten C, Phillips EM, Frontera WR and Fielding RA. Comparative effects of light or heavy resistance power training for improving lower extremity power and physical performance in mobility-limited older adults. J Gerontol A Biol Sci Med Sci, 70(3):374-80, 2015.
Clark DJ, Rose DK, Ring SA and Porges EC. Utilization of central nervous system resources for preparation and performance of complex walking tasks in older adults. Front Aging Neurosci, 6:217, 2014.
Clark DJ, Christou EA, Ring SA, Williamson JB and Doty L. Enhanced somatosensory feedback reduces prefrontal cortical activity during walking in older adults. J Gerontol A Biol Sci Med Sci, in press.
Reid KF, Martin KI, Doros G, Clark DJ, Hau C, Patten C, Phillips EM, Frontera WR and Fielding RA. Comparative effects of light or heavy resistance power training for improving lower extremity power and physical performance in mobility-limited older adults. J Gerontol A Biol Sci Med Sci, in press.
Balasubramanian CK, Clark DJ, Fox EJ. Walking adaptability after a stroke and its assessment in clinical settings. Stroke Res Treat, in press.
Cruz-Almeida Y, Black ML, Christou EA and Clark DJ. Site-specific differences in the association between plantar tactile perception and mobility function in older adults. Front Aging Neurosci, 6:68, 2014.
Clark DJ, Reid KF, Patten C, Phillips EM, Ring SA, Wu SS and Fielding RA. Does quadriceps neuromuscular activation capability explain walking speed among older men and women? Exp Gerontol, 55: 49-53, 2014.
Buford TW, Anton SD, Clark DJ, Higgins TJ and Cooke MB. Optimizing the benefits of exercise on physical function in older adults. PM&R, in press.
Reid KF, Pasha EP, Doros G, Clark DJ, Patten C, Phillips EM, Frontera WR and Fielding RA. Longitudinal decline of lower extremity muscle power in healthy and mobility-limited older adults: influence of muscle mass, strength, composition, neuromuscular activation and single fiber contractile properties. Eur J Appl Physiol, in press.
Fox EJ, Tester NJ, Kautz SA, Howland DR, Clark DJ, Garvan C, and Behrman AL. Neuromuscular control across locomotor tasks in children with incomplete spinal cord injuries. J Neurophys, 110(6): 1415-25, 2013.
Clark DJ, Kautz SA, Bauer AR, Chen YT and Christou SA. Synchronous EMG activity in the Piper frequency band reveals the corticospinal demand of walking tasks. Ann Biomed Eng, 41(8): 1778-1786, 2013.
Clark DJ, Pojednic RM, Reid KF, Patten C, Pasha EP, Phillips EM and Fielding RA. Longitudinal decline of neuromuscular activation and power in healthy older adults. J Gerontol A Biol Sci Med Sci, in press.
Routson RL, Clark DJ, Bowden MG, Kautz SA and Neptune RR. The influence of locomotor rehabilitation on module quality and post-stroke hemiparetic walking performance. Gait and Posture, in press.
Clark DJ, Manini TM, Fielding RA and Patten C. Neuromuscular determinants of maximum walking speed in well-functioning older adults. Exp Gerontol, 48(3):358-363, 2013.
Clark DJ and Patten C. Eccentric versus concentric resistance training to enhance neuromuscular activation and walking speed following stroke. Neurorehabil Neural Repair, in press.
Reid KF, Doros G, Clark DJ, Patten C, Carabello RJ, Cloutier GJ, Phillips EM, Krivickas L, Frontera W and Fielding RA. Muscle power failure in mobility-limited older adults: preserved single fiber function despite lower whole muscle size, quality and rate of neuromuscular activation. Eur J Appl Physiol, 112(6): 2289-301, 2012.
Clark DJ, Fielding RA. Neuromuscular contributions to age-related weakness. J Gerontol A Biol Sci Med Sci, 67(1): 41-7, 2012.
Kautz SA, Bowden MG, Clark DJ and Neptune RR. Comparison of motor control deficits during treadmill and overground walking post-stroke. Neurorehabil Neural Repair, 25(8): 756-65, 2011.
Clark DJ, Patten C, Reid KF, Carabello RJ, Phillips EM and Fielding RA. Muscle performance and physical function are associated with voluntary rate of neuromuscular activation in older adults. J Gerontol A Biol Sci Med Sci, 66(1): 115-21, 2011.
Clark DJ, Patten C, Reid KF, Carabello RJ, Phillips EM and Fielding RA. Impaired voluntary neuromuscular activation limits muscle power in mobility-limited older adults. J Gerontol A Biol Sci Med Sci, 65(5): 495-502, 2010.
Clark DJ, Ting LH, Zajac FE, Neptune RR and Kautz SA. Merging of healthy motor modules predicts reduced locomotor performance and muscle coordination complexity post-stroke. J Neurophys, 103(2): 844-57, 2010.
McGowan CP, Neptune RR, Clark DJ and Kautz SA. Modular control of human walking: Adaptations to altered mechanical demand. J Biomech, 43(3): 412-419, 2010.
Carabello RJ, Reid KF, Clark DJ, Phillips EM and Fielding RA. Lower extremity strength and power asymmetry assessment in healthy and mobility-limited populations: reliability and association with physical functioning. Aging Clin Exp Res, 22(4): 324-9, 2010.
Bowden MG, Clark DJ, Neptune RR and Kautz SA. Evaluation of abnormal synergy patterns post-stroke: relationship of clinical examination to hemiparetic locomotion. Neurorehabil Neural Repair, 24(4): 328-37, 2010.
Neptune RR, Clark DJ and Kautz, SA. Modular control of human walking: a simulation study. J Biomech, 42(9): 1282-7, 2009.
Clark DJ, Condliffe EG, Patten C. Activation impairment alters muscle-torque velocity in the knee extensors of persons with post-stroke hemiparesis. Clin Neurophysiol, 117(10): 2328-37, 2006.
Clark DJ, Condliffe EG, Patten C. Reliability of concentric and eccentric torque during isokinetic knee extension in post-stroke hemiparesis. Clin Biomech, 21: 395-404, 2006.
Condliffe EG, Clark DJ, Patten C. Reliability of elbow stretch reflex assessment in chronic post-stroke hemiparesis. Clin Neurophysiol, 116: 1870-8, 2005.