David J Clark

David J Clark, Sc.D.

Associate Professor

Department: MD-AGING-CLINICAL RESEARCH
Business Phone: (352) 376-1611
Business Email: davidclark@ufl.edu

About David J Clark

My research focuses on enhancing walking function in people with neurological impairments, particularly older adults and people post-stroke. Ongoing studies involve neurorehabilitation, neuroimaging, non-invasive brain stimulation, electrophysiology, and biomechanics. Grant funding listed below includes only projects administered by UF. For a full listing (including funding from the US Dept of Veterans Affairs) please see the attached curriculum vitae. Publications from my lab group are available at the following links for Pubmed and Google Scholar.

Accomplishments

PECASE (Presidential Early Career Award for Scientists and Engineers)
2019 · The White House

Publications

2021
Does falls efficacy influence the relationship between forward and backward walking speed after stroke?
Physical therapy. [DOI] 10.1093/ptj/pzab050. [PMID] 33561276.
2021
Rehabilitation with accurate adaptability walking tasks or steady state walking: A randomized clinical trial in adults post-stroke.
Clinical rehabilitation. [DOI] 10.1177/02692155211001682. [PMID] 33722075.
2020
A consensus guide to using functional near-infrared spectroscopy in posture and gait research.
Gait & posture. 82:254-265 [DOI] 10.1016/j.gaitpost.2020.09.012. [PMID] 32987345.
2020
A Cross-species Model of Dual-Task Walking in Young and Older Humans and Rats.
Frontiers in aging neuroscience. 12 [DOI] 10.3389/fnagi.2020.00276. [PMID] 32982717.
2020
Combining Frontal Transcranial Direct Current Stimulation With Walking Rehabilitation to Enhance Mobility and Executive Function: A Pilot Clinical Trial.
Neuromodulation : journal of the International Neuromodulation Society. [DOI] 10.1111/ner.13250. [PMID] 32808403.
2020
Corrigendum: Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods.
Frontiers in aging neuroscience. 12 [DOI] 10.3389/fnagi.2020.00063. [PMID] 32194394.
2020
Innovations in Geroscience to enhance mobility in older adults.
Experimental gerontology. 142 [DOI] 10.1016/j.exger.2020.111123. [PMID] 33191210.
2020
Obstacle Negotiation in Older Adults: Prefrontal Activation Interpreted Through Conceptual Models of Brain Aging.
Innovation in aging. 4(4) [DOI] 10.1093/geroni/igaa034. [PMID] 32995566.
2019
A Perspective on Objective Measurement of the Perceived Challenge of Walking.
Frontiers in human neuroscience. 13 [DOI] 10.3389/fnhum.2019.00161. [PMID] 31139069.
2019
Assessment of backward walking unmasks mobility impairments in post-stroke community ambulators.
Topics in stroke rehabilitation. 26(5):382-388 [DOI] 10.1080/10749357.2019.1609182. [PMID] 31081491.
2018
A Backward Walking Training Program to Improve Balance and Mobility in Acute Stroke: A Pilot Randomized Controlled Trial.
Journal of neurologic physical therapy : JNPT. 42(1):12-21 [DOI] 10.1097/NPT.0000000000000210. [PMID] 29232308.
2018
Addressing limitations of the Gait Variability Index to enhance its applicability: The enhanced GVI (EGVI).
PloS one. 13(6) [DOI] 10.1371/journal.pone.0198267. [PMID] 29856818.
2018
Dynamic balance during walking adaptability tasks in individuals post-stroke.
Journal of biomechanics. 74:106-115 [DOI] 10.1016/j.jbiomech.2018.04.029. [PMID] 29724539.
2018
Mobility Function and Recovery After Stroke: Preliminary Insights From Sympathetic Nervous System Activity.
Journal of neurologic physical therapy : JNPT. 42(4):224-232 [DOI] 10.1097/NPT.0000000000000238. [PMID] 30138228.
2018
Prefrontal over-activation during walking in people with mobility deficits: Interpretation and functional implications.
Human movement science. 59:46-55 [DOI] 10.1016/j.humov.2018.03.010. [PMID] 29604488.
2018
Sympathetic nervous system activity measured by skin conductance quantifies the challenge of walking adaptability tasks after stroke.
Gait & posture. 60:148-153 [DOI] 10.1016/j.gaitpost.2017.11.025. [PMID] 29216598.
2017
EMG synchrony to assess impaired corticomotor control of locomotion after stroke.
Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology. 37:35-40 [DOI] 10.1016/j.jelekin.2017.08.007. [PMID] 28888972.
2017
Walking on uneven terrain in healthy adults and the implications for people after stroke.
NeuroRehabilitation. 41(4):765-774 [DOI] 10.3233/NRE-172154. [PMID] 28946584.
2016
Locomotor Adaptability Task Promotes Intense and Task-Appropriate Output From the Paretic Leg During Walking.
Archives of physical medicine and rehabilitation. 97(3):493-6 [DOI] 10.1016/j.apmr.2015.10.081. [PMID] 26525528.
2015
Aging, the Central Nervous System, and Mobility in Older Adults: Neural Mechanisms of Mobility Impairment.
The journals of gerontology. Series A, Biological sciences and medical sciences. 70(12):1526-32 [DOI] 10.1093/gerona/glv130. [PMID] 26386013.
2015
Automaticity of walking: functional significance, mechanisms, measurement and rehabilitation strategies.
Frontiers in human neuroscience. 9 [DOI] 10.3389/fnhum.2015.00246. [PMID] 25999838.
2015
Comparative effects of light or heavy resistance power training for improving lower extremity power and physical performance in mobility-limited older adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 70(3):374-80 [DOI] 10.1093/gerona/glu156. [PMID] 25199912.
2015
Successful Aging: Advancing the Science of Physical Independence in Older Adults
Ageing Research Reviews. 24(B):304-327 [DOI] 10.1016/j.arr.2015.09.005. [PMID] 26462882.
2015
Successful aging: Advancing the science of physical independence in older adults.
Ageing research reviews. 24(Pt B):304-27 [DOI] 10.1016/j.arr.2015.09.005. [PMID] 26462882.
2015
Validity of the gait variability index in older adults: effect of aging and mobility impairments.
Gait & posture. 41(4):941-6 [DOI] 10.1016/j.gaitpost.2015.03.349. [PMID] 25882115.
2014
Does quadriceps neuromuscular activation capability explain walking speed in older men and women?
Experimental gerontology. 55:49-53 [DOI] 10.1016/j.exger.2014.03.019. [PMID] 24703887.
2014
Enhanced somatosensory feedback reduces prefrontal cortical activity during walking in older adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 69(11):1422-8 [DOI] 10.1093/gerona/glu125. [PMID] 25112494.
2014
Longitudinal decline of lower extremity muscle power in healthy and mobility-limited older adults: influence of muscle mass, strength, composition, neuromuscular activation and single fiber contractile properties.
European journal of applied physiology. 114(1):29-39 [PMID] 24122149.
View on: PubMed
2014
Optimizing the benefits of exercise on physical function in older adults.
PM & R : the journal of injury, function, and rehabilitation. 6(6):528-43 [DOI] 10.1016/j.pmrj.2013.11.009. [PMID] 24361365.
2014
Site-specific differences in the association between plantar tactile perception and mobility function in older adults.
Frontiers in aging neuroscience. 6 [DOI] 10.3389/fnagi.2014.00068. [PMID] 24782765.
2014
Utilization of central nervous system resources for preparation and performance of complex walking tasks in older adults.
Frontiers in aging neuroscience. 6 [DOI] 10.3389/fnagi.2014.00217. [PMID] 25202270.
2014
Walking adaptability after a stroke and its assessment in clinical settings.
Stroke research and treatment. 2014 [DOI] 10.1155/2014/591013. [PMID] 25254140.
2013
Eccentric versus concentric resistance training to enhance neuromuscular activation and walking speed following stroke.
Neurorehabilitation and neural repair. 27(4):335-44 [DOI] 10.1177/1545968312469833. [PMID] 23292848.
2013
Longitudinal decline of neuromuscular activation and power in healthy older adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 68(11):1419-25 [DOI] 10.1093/gerona/glt036. [PMID] 23676250.
2013
Modular control of varied locomotor tasks in children with incomplete spinal cord injuries.
Journal of neurophysiology. 110(6):1415-25 [DOI] 10.1152/jn.00676.2012. [PMID] 23761702.
2013
Neuromuscular determinants of maximum walking speed in well-functioning older adults.
Experimental gerontology. 48(3):358-63 [DOI] 10.1016/j.exger.2013.01.010. [PMID] 23376102.
2013
Synchronous Electromyogram Activity Reveals the Cns Contribution To Mobility Tasks in Older Adults
Gerontologist. 53(1)
2013
Synchronous EMG activity in the piper frequency band reveals the corticospinal demand of walking tasks.
Annals of biomedical engineering. 41(8):1778-86 [DOI] 10.1007/s10439-013-0832-4. [PMID] 23740367.
2013
The influence of locomotor rehabilitation on module quality and post-stroke hemiparetic walking performance.
Gait & posture. 38(3):511-7 [DOI] 10.1016/j.gaitpost.2013.01.020. [PMID] 23489952.
2012
Muscle power failure in mobility-limited older adults: preserved single fiber function despite lower whole muscle size, quality and rate of neuromuscular activation.
European journal of applied physiology. 112(6):2289-301 [DOI] 10.1007/s00421-011-2200-0. [PMID] 22005960.
2012
Neuromuscular contributions to age-related weakness.
The journals of gerontology. Series A, Biological sciences and medical sciences. 67(1):41-7 [DOI] 10.1093/gerona/glr041. [PMID] 21415261.
2012
The specific contributions of force and velocity to muscle power in older adults.
Experimental gerontology. 47(8):608-13 [DOI] 10.1016/j.exger.2012.05.010. [PMID] 22626972.
2011
Comparison of motor control deficits during treadmill and overground walking poststroke.
Neurorehabilitation and neural repair. 25(8):756-65 [DOI] 10.1177/1545968311407515. [PMID] 21636831.
2010
Evaluation of abnormal synergy patterns poststroke: relationship of the Fugl-Meyer Assessment to hemiparetic locomotion.
Neurorehabilitation and neural repair. 24(4):328-37 [DOI] 10.1177/1545968309343215. [PMID] 19794132.
2010
Impaired voluntary neuromuscular activation limits muscle power in mobility-limited older adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 65(5):495-502 [DOI] 10.1093/gerona/glq012. [PMID] 20156882.
2010
Lower extremity strength and power asymmetry assessment in healthy and mobility-limited populations: reliability and association with physical functioning.
Aging clinical and experimental research. 22(4):324-9 [DOI] 10.3275/6676. [PMID] 19940556.
2010
Merging of healthy motor modules predicts reduced locomotor performance and muscle coordination complexity post-stroke.
Journal of neurophysiology. 103(2):844-57 [DOI] 10.1152/jn.00825.2009. [PMID] 20007501.
2010
Modular control of human walking: Adaptations to altered mechanical demands.
Journal of biomechanics. 43(3):412-9 [DOI] 10.1016/j.jbiomech.2009.10.009. [PMID] 19879583.
2009
Modular control of human walking: a simulation study.
Journal of biomechanics. 42(9):1282-7 [DOI] 10.1016/j.jbiomech.2009.03.009. [PMID] 19394023.
2006
Activation impairment alters muscle torque-velocity in the knee extensors of persons with post-stroke hemiparesis.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 117(10):2328-37 [PMID] 16926111.
View on: PubMed
2006
Reliability of concentric and eccentric torque during isokinetic knee extension in post-stroke hemiparesis.
Clinical biomechanics (Bristol, Avon). 21(4):395-404 [PMID] 16403594.
View on: PubMed
2005
Reliability of elbow stretch reflex assessment in chronic post-stroke hemiparesis.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 116(8):1870-8 [PMID] 15979400.
View on: PubMed

Grants

Oct 2018 ACTIVE
National Resource Center for High-Impact Clinical Trials in Medical Rehabilitation: Pilot Projects Component
Role: Co-Investigator
Funding: UNIV OF ALABAMA BIRMINGHAM via NATL INST OF HLTH NICHD
Sep 2018 ACTIVE
Multimodal imaging of brain activity to investigate walking and mobility decline in older adults
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Jul 2018 – Jun 2020
Neuromodulation of spinal circuits to enhance practice-related performance on a complex walking task (Pilot Project).
Role: Co-Investigator
Funding: MEDICAL UNIV OF SOUTH CAROLINA via NATL INST OF HLTH NICHD
Jun 2017 – May 2020
Combining tDCS and neurorehabilitation to treat age-related deficits of mobility and cognition
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA

Education

Doctor of Science in Rehabilitation Sciences
2007 · Boston University
Bachelors of Science in Exercise Physiology
2001 · University of Massachusetts-Lowell

Teaching Profile

Courses Taught
2018
GMS7980 Research for Doctoral Dissertation
2018
BMS6812 Intro Clin Med 2
2016-2017
RSD7980 Research for Doctoral Dissertation
2017
RSD6930 Special Topics in Rehabilitation Science
2016
RSD7979 Advanced Research
2015
RSD6910 Supervised Research
2015
RSD6905 Individual Work

Contact Details

Phones:
Business:
(352) 376-1611
Emails:
Business:
davidclark@ufl.edu